deltatrials
Terminated PHASE2 INTERVENTIONAL 5-arm NCT05999799

A Dose Finding Study to Investigate the Safety and Effectiveness of GSK1070806 in Adult Participants With Moderate to Severe Atopic Dermatitis (AtDventure)

A Phase 2b, Randomized, Double-Blind, Parallel Group, Placebo Controlled, Dose Finding Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of GSK1070806 SC Injection in Adult Participants With Moderate to Severe Atopic Dermatitis

Sponsor: GlaxoSmithKline

Updated 19 times since 2023 Last updated: Nov 14, 2025 Started: Nov 16, 2023 Primary completion: Jul 23, 2025 Completion: Jul 23, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Sponsor decision to early terminate the study based on the pre-defined futility criterion for efficacy. No safety concerns were identified.

This PHASE2 trial investigates Dermatitis, Atopic and is currently terminated or withdrawn. GlaxoSmithKline leads this study, which shows 19 recorded versions since 2023 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Sep 2023 – ~Jan 2024 · 4 months · monthly snapshotNot Yet Recruiting~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Jun 2024 · 3 months · monthly snapshotRecruiting~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Jan 2025 · 2 months · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Apr 2025 · 59 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshotActive Not Recruiting~Dec 2025 – present · 8 months · monthly snapshotTerminated

Change History

19 versions recorded
  1. Dec 2025 — Present [monthly]

    Terminated PHASE2

    Status: Active Not RecruitingTerminated

  2. Sep 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE2

  5. Jun 2025 — Jul 2025 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

Show 14 earlier versions
  1. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE2

  2. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE2

  3. Feb 2025 — Apr 2025 [monthly]

    Recruiting PHASE2

  4. Jan 2025 — Feb 2025 [monthly]

    Recruiting PHASE2

  5. Nov 2024 — Jan 2025 [monthly]

    Recruiting PHASE2

  6. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE2

  7. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE2

  8. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  9. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2

  10. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  11. Mar 2024 — Jun 2024 [monthly]

    Recruiting PHASE2

  12. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE2

  13. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  14. Sep 2023 — Jan 2024 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • GlaxoSmithKline
Data source: GlaxoSmithKline

For direct contact, visit the study record on ClinicalTrials.gov .