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Completed PHASE3 INTERVENTIONAL 2-arm NCT01332968

A Study of Obinutuzumab (RO5072759) Plus Chemotherapy in Comparison With Rituximab Plus Chemotherapy Followed by Obinutuzumab or Rituximab Maintenance in Patients With Untreated Advanced Indolent Non-Hodgkin's Lymphoma (GALLIUM)

A Multicenter, Phase III, Open-Label, Randomized Study in Previously Untreated Patients With Advanced Indolent Non-Hodgkin's Lymphoma Evaluating the Benefit of GA101 (RO5072759) Plus Chemotherapy Compared With Rituximab Plus Chemotherapy Followed by GA101 or Rituximab Maintenance Therapy in Responders

Sponsor: German Low Grade Lymphoma Study Group

Updated 25 times since 2017 Last updated: Aug 9, 2022 Started: Jul 6, 2011 Primary completion: Feb 1, 2016 Completion: Jul 30, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01332968, this PHASE3 trial focuses on Non-Hodgkin's Lymphoma and remains completed. Sponsored by German Low Grade Lymphoma Study Group, it has been updated 25 times since 2011, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshot~Jul 2017 – ~Jan 2018 · 6 months · monthly snapshot~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Oct 2018 · 2 months · monthly snapshot~Oct 2018 – ~Jan 2019 · 3 months · monthly snapshot~Jan 2019 – ~May 2019 · 4 months · monthly snapshot~May 2019 – ~Aug 2019 · 3 months · monthly snapshot~Aug 2019 – ~Nov 2019 · 3 months · monthly snapshot~Nov 2019 – ~Feb 2020 · 3 months · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Jul 2020 · 2 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Jan 2022 · 2 months · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Jun 2022 · 4 months · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

25 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Sep 2022 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2022 — Sep 2022 [monthly]

    Completed PHASE3

Show 20 earlier versions
  1. Feb 2022 — Jun 2022 [monthly]

    Completed PHASE3

  2. Jan 2022 — Feb 2022 [monthly]

    Completed PHASE3

  3. Nov 2021 — Jan 2022 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  4. Sep 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE3

  5. May 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE3

  6. Jan 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE3

  7. Jul 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  8. May 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE3

  9. Feb 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE3

  10. Nov 2019 — Feb 2020 [monthly]

    Active Not Recruiting PHASE3

  11. Aug 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE3

  12. May 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE3

  13. Jan 2019 — May 2019 [monthly]

    Active Not Recruiting PHASE3

  14. Oct 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE3

  15. Aug 2018 — Oct 2018 [monthly]

    Active Not Recruiting PHASE3

  16. Jun 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE3

  17. Jan 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

  18. Jul 2017 — Jan 2018 [monthly]

    Active Not Recruiting PHASE3

  19. Feb 2017 — Jul 2017 [monthly]

    Active Not Recruiting PHASE3

  20. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Jul 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • German Low Grade Lymphoma Study Group
  • Hoffmann-La Roche
  • Institute of Cancer Research, United Kingdom
Data source: Hoffmann-La Roche

For direct contact, visit the study record on ClinicalTrials.gov .