deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT01381718

Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

A Phase II Placebo-Controlled Trial of Modafinil to Improve Neurocognitive Deficits in Children Treated for a Primary Brain Tumor

Sponsor: National Cancer Institute (NCI)

Updated 11 times since 2017 Last updated: Jul 20, 2021 Started: Aug 31, 2011 Primary completion: Aug 31, 2016 Completion: Aug 31, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01381718, this PHASE2 trial focuses on Brain and Central Nervous System Tumors and Cognitive/Functional Effects and remains completed. Sponsored by National Cancer Institute (NCI), it has been updated 11 times since 2011, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshotActive Not Recruiting~Aug 2017 – ~Nov 2017 · 3 months · monthly snapshotActive Not Recruiting~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshotCompleted~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshotCompleted~Oct 2018 – ~Jan 2021 · 27 months · monthly snapshotCompleted~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotCompleted~Feb 2021 – ~Sep 2021 · 7 months · monthly snapshotCompleted~Sep 2021 – ~Jul 2024 · 34 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Sep 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Feb 2021 — Sep 2021 [monthly]

    Completed PHASE2

Show 6 earlier versions
  1. Jan 2021 — Feb 2021 [monthly]

    Completed PHASE2

  2. Oct 2018 — Jan 2021 [monthly]

    Completed PHASE2

  3. Jun 2018 — Oct 2018 [monthly]

    Completed PHASE2

  4. Nov 2017 — Jun 2018 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  5. Aug 2017 — Nov 2017 [monthly]

    Active Not Recruiting PHASE2

  6. Jan 2017 — Aug 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Aug 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • University of South Florida
Data source: University of South Florida

For direct contact, visit the study record on ClinicalTrials.gov .