deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT01404754

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-1)

A Phase 1 Placebo-Controlled, Double-Blind Crossover Study to Assess Psychological Effects of MDMA When Administered to Healthy Volunteers

Sponsor: Lykos Therapeutics

Conditions Psychological Effects of Study Drug
Interventions Lactose (inactive placebo) midomafetamine HCl
Updated 24 times since 2017 Last updated: Oct 29, 2024 Started: Apr 9, 2011 Primary completion: Aug 5, 2022 Completion: Aug 5, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Psychological Effects of Study Drug, this trial is completed. The trial is conducted by Lykos Therapeutics and has accumulated 24 data snapshots since 2011. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Jan 2019 · 5 months · monthly snapshot~Jan 2019 – ~Jun 2019 · 5 months · monthly snapshot~Jun 2019 – ~Sep 2019 · 3 months · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Mar 2020 · 4 months · monthly snapshot~Mar 2020 – ~Jul 2020 · 4 months · monthly snapshot~Jul 2020 – ~Dec 2020 · 5 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Jun 2022 · 4 months · monthly snapshot~Jun 2022 – ~Nov 2022 · 5 months · monthly snapshot~Nov 2022 – ~May 2023 · 6 months · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jan 2024 · 7 months · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Sep 2025 · 10 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

24 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Nov 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Sep 2024 — Nov 2024 [monthly]

    Completed PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  5. Feb 2024 — Jul 2024 [monthly]

    Completed PHASE1

▶ Show 19 earlier versions

  1. Jan 2024 — Feb 2024 [monthly]

    Completed PHASE1

  2. Jun 2023 — Jan 2024 [monthly]

    Completed PHASE1

  3. May 2023 — Jun 2023 [monthly]

    Completed PHASE1

  4. Nov 2022 — May 2023 [monthly]

    Completed PHASE1

    Status: Enrolling By Invitation → Completed

  5. Jun 2022 — Nov 2022 [monthly]

    Enrolling By Invitation PHASE1

  6. Feb 2022 — Jun 2022 [monthly]

    Enrolling By Invitation PHASE1

  7. Sep 2021 — Feb 2022 [monthly]

    Enrolling By Invitation PHASE1

  8. Jan 2021 — Sep 2021 [monthly]

    Enrolling By Invitation PHASE1

  9. Dec 2020 — Jan 2021 [monthly]

    Enrolling By Invitation PHASE1

  10. Jul 2020 — Dec 2020 [monthly]

    Enrolling By Invitation PHASE1

  11. Mar 2020 — Jul 2020 [monthly]

    Enrolling By Invitation PHASE1

  12. Nov 2019 — Mar 2020 [monthly]

    Enrolling By Invitation PHASE1

  13. Sep 2019 — Nov 2019 [monthly]

    Enrolling By Invitation PHASE1

  14. Jun 2019 — Sep 2019 [monthly]

    Enrolling By Invitation PHASE1

  15. Jan 2019 — Jun 2019 [monthly]

    Enrolling By Invitation PHASE1

  16. Aug 2018 — Jan 2019 [monthly]

    Enrolling By Invitation PHASE1

  17. Jun 2018 — Aug 2018 [monthly]

    Enrolling By Invitation PHASE1

  18. Feb 2017 — Jun 2018 [monthly]

    Enrolling By Invitation PHASE1

  19. Jan 2017 — Feb 2017 [monthly]

    Enrolling By Invitation PHASE1

    First recorded

Apr 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Lykos Therapeutics
Data source: Lykos Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations