deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 3-arm NCT01422772

Safety Study of Gene Therapy for Ischemic Heart Disease in Korea (Engensis)

Open-label, Non-comparative, Dose-escalation, Single-center, Phase 1 Trial to Evaluate the Safety of VM202RY Gene Medicine Injected Into Cardiac Muscle of Incompletely Revascularized Area After CABG in Patients With Ischemic Heart Diseases

Sponsor: Helixmith Co., Ltd.

Updated 10 times since 2017 Last updated: Sep 11, 2025 Started: Jan 31, 2007 Primary completion: Feb 28, 2010 Completion: Aug 31, 2014
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Ischemic Heart Disease, this trial is completed. The trial is conducted by Helixmith Co., Ltd. and has accumulated 10 data snapshots since 2007. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

~Jan 2017 – ~Feb 2018 · 13 months · monthly snapshotCompleted~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshotCompleted~Jun 2018 – ~Jun 2019 · 12 months · monthly snapshotCompleted~Jun 2019 – ~Nov 2019 · 5 months · monthly snapshotCompleted~Nov 2019 – ~Jan 2021 · 14 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshotCompleted~Nov 2025 – present · 8 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Nov 2025 — Present [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1PHASE1/PHASE2

  2. Sep 2025 — Nov 2025 [monthly]

    Completed PHASE1

  3. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  5. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

Show 5 earlier versions
  1. Nov 2019 — Jan 2021 [monthly]

    Completed PHASE1

  2. Jun 2019 — Nov 2019 [monthly]

    Completed PHASE1

  3. Jun 2018 — Jun 2019 [monthly]

    Completed PHASE1

  4. Feb 2018 — Jun 2018 [monthly]

    Completed PHASE1

  5. Jan 2017 — Feb 2018 [monthly]

    Completed PHASE1

    First recorded

Jan 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Helixmith Co., Ltd.
Data source: Helixmith Co., Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations