Terminated PHASE3 INTERVENTIONAL 2-arm NCT01459796

Study of the Safety and Efficacy of Long-Term Rilonacept Treatment for the Prevention of Gout Flares (UPSURGE)

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Long-Term Rilonacept Treatment for the Prevention of Gout Flares

Sponsor: Regeneron Pharmaceuticals

Conditions Gout

Interventions Allopurinol Placebo Rilonacept

Updated 8 times since 2017 Last updated: Jun 19, 2017 Started: Nov 30, 2011 Primary completion: Jun 30, 2013 Completion: Jun 30, 2013

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This trial was terminated. No reason was provided.

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Listed as NCT01459796, this PHASE3 trial focuses on Gout and remains terminated or withdrawn. Sponsored by Regeneron Pharmaceuticals, it has been updated 8 times since 2011, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Terminated PHASE3
Sep 2024 — Sep 2025 [monthly]

Terminated PHASE3
Jul 2024 — Sep 2024 [monthly]

Terminated PHASE3
Jan 2021 — Jul 2024 [monthly]

Terminated PHASE3
Jun 2018 — Jan 2021 [monthly]

Terminated PHASE3

▶ Show 3 earlier versions

Aug 2017 — Jun 2018 [monthly]

Terminated PHASE3
Feb 2017 — Aug 2017 [monthly]

Terminated PHASE3
Jan 2017 — Feb 2017 [monthly]

Terminated PHASE3

First recorded

Nov 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Regeneron Pharmaceuticals

Data source: Regeneron Pharmaceuticals

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Akron, United States , Anderson, United States , Arlington, United States , Atlanta, United States , Avon, United States , Birmingham, United States , Boise, United States , Bowling Green, United States , Brooklyn, United States , Brownsburg, United States and 63 more locations