deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 1-arm NCT01463072

Nab-Paclitaxel in Treating Older Patients With Locally Advanced or Metastatic Breast Cancer

Efficacy and Tolerability of Nanoparticle Albumin Bound Paclitaxel (Abraxane) in Patients 65 and Older With Locally Advanced or Metastatic Breast Cancer

Sponsor: City of Hope Medical Center

Conditions Locally Advanced Breast Carcinoma Metastatic Breast Carcinoma Recurrent Breast Carcinoma Stage III Breast Cancer AJCC v7 Stage IIIA Breast Cancer AJCC v7 Stage IIIB Breast Cancer AJCC v7 Stage IIIC Breast Cancer AJCC v7 Stage IV Breast Cancer AJCC v6 and v7
Interventions Laboratory Biomarker Analysis Nab-paclitaxel Questionnaire Administration
Updated 20 times since 2017 Last updated: Jul 16, 2025 Started: Jun 19, 2012 Primary completion: May 17, 2017 Completion: May 18, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01463072, this PHASE2 trial focuses on Locally Advanced Breast Carcinoma and Metastatic Breast Carcinoma and remains ongoing. Sponsored by City of Hope Medical Center, it has been updated 20 times since 2012, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Sep 2017 · 7 months · monthly snapshot~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshot~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshot~Oct 2018 – ~Oct 2019 · 12 months · monthly snapshot~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshot~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Mar 2023 · 59 days · monthly snapshot~Mar 2023 – ~Sep 2023 · 6 months · monthly snapshot~Sep 2023 – ~Mar 2024 · 6 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~Aug 2025 · 5 months · monthly snapshot~Aug 2025 – present · 12 months · monthly snapshot

Change History

20 versions recorded

  1. Aug 2025 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Mar 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Sep 2024 — Mar 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

▶ Show 15 earlier versions

  1. Sep 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Mar 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

  3. Jan 2023 — Mar 2023 [monthly]

    Active Not Recruiting PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Active Not Recruiting PHASE2

  5. Sep 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE2

  6. Sep 2021 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2

  7. Mar 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  8. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE2

  9. Dec 2019 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  10. Oct 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE2

  11. Oct 2018 — Oct 2019 [monthly]

    Active Not Recruiting PHASE2

  12. Jun 2018 — Oct 2018 [monthly]

    Active Not Recruiting PHASE2

  13. Sep 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  14. Feb 2017 — Sep 2017 [monthly]

    Active Not Recruiting PHASE2

  15. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Jun 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • City of Hope Medical Center
  • National Cancer Institute (NCI)
Data source: City of Hope Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations