deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT01475162

Tocilizumab for Treatment of Steroid Refractory Acute Graft-versus-Host Disease

Phase I-II Study Using Tocilizumab for Treatment of Steroid Refractory Acute Graft-versus-Host Disease

Sponsor: Medical College of Wisconsin

Interventions Tocilizumab
Updated 10 times since 2017 Last updated: Jan 30, 2020 Started: Aug 8, 2011 Primary completion: Feb 17, 2016 Completion: Sep 29, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The DSMB felt the risks of the study now outweighed the potential benefits.

Listed as NCT01475162, this PHASE1/PHASE2 trial focuses on Acute Graft Versus Host Disease and remains terminated or withdrawn. Sponsored by Medical College of Wisconsin, it has been updated 10 times since 2011, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshotTerminated~Aug 2017 – ~Mar 2018 · 7 months · monthly snapshotTerminated~Mar 2018 – ~May 2018 · 2 months · monthly snapshotTerminated~May 2018 – ~Jun 2018 · 31 days · monthly snapshotTerminated~Jun 2018 – ~Feb 2020 · 20 months · monthly snapshotTerminated~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshotTerminated~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshotTerminated~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 23 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

  4. Mar 2020 — Jan 2021 [monthly]

    Terminated PHASE1_PHASE2

  5. Feb 2020 — Mar 2020 [monthly]

    Terminated PHASE1_PHASE2

Show 5 earlier versions
  1. Jun 2018 — Feb 2020 [monthly]

    Terminated PHASE1_PHASE2

  2. May 2018 — Jun 2018 [monthly]

    Terminated PHASE1_PHASE2

  3. Mar 2018 — May 2018 [monthly]

    Terminated PHASE1_PHASE2

  4. Aug 2017 — Mar 2018 [monthly]

    Terminated PHASE1_PHASE2

  5. Jan 2017 — Aug 2017 [monthly]

    Terminated PHASE1_PHASE2

    First recorded

Aug 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Medical College of Wisconsin
Data source: Medical College of Wisconsin

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations