deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 3-arm NCT01494805

Safety and Efficacy Study of rAAV.sFlt-1 in Patients With Exudative Age-Related Macular Degeneration (AMD)

A Phase I/II Controlled Dose-escalating Trial to Establish the Baseline Safety and Efficacy of a Single Subretinal Injection of rAAV.sFlt-1 Into Eyes of Patients With Exudative Age-related Macular Degeneration (AMD)

Sponsor: Adverum Biotechnologies, Inc.

Updated 8 times since 2017 Last updated: Aug 30, 2017 Started: Dec 31, 2011 Primary completion: May 31, 2017 Completion: Aug 31, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Age-related Maculopathies and Age-related Maculopathy, this trial is completed. The trial is conducted by Adverum Biotechnologies, Inc. and has accumulated 8 data snapshots since 2011. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshotActive Not Recruiting~Jun 2017 – ~Sep 2017 · 3 months · monthly snapshotUnknown Status~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

  5. Sep 2017 — Jun 2018 [monthly]

    Completed PHASE1_PHASE2

    Status: Unknown StatusCompleted

Show 3 earlier versions
  1. Jun 2017 — Sep 2017 [monthly]

    Unknown Status PHASE1_PHASE2

    Status: Active Not RecruitingUnknown Status

  2. Feb 2017 — Jun 2017 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  3. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    First recorded

Dec 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Adverum Biotechnologies, Inc.
  • Lions Eye Institute, Perth, Western Australia
Data source: Lions Eye Institute, Perth, Western Australia

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations