deltatrials
Recruiting PHASE3 INTERVENTIONAL 2-arm NCT06856577

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration (ARTEMIS)

A Multi-Center, Randomized, Double-Masked, Active-Comparator-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration (ARTEMIS)

Sponsor: Adverum Biotechnologies, Inc.

Updated 9 times since 2025 Last updated: Nov 15, 2025 Started: Feb 28, 2025 Primary completion: Dec 22, 2026 Completion: Nov 23, 2030
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT06856577, this PHASE3 trial focuses on Neovascular Age-Related Macular Degeneration (nAMD) and Wet AMD and remains actively recruiting participants. Sponsored by Adverum Biotechnologies, Inc., it has been updated 9 times since 2025, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshotRecruiting

Change History

9 versions recorded
  1. Dec 2025 — Present [monthly]

    Recruiting PHASE3

  2. Nov 2025 — Dec 2025 [monthly]

    Recruiting PHASE3

  3. Oct 2025 — Nov 2025 [monthly]

    Recruiting PHASE3

  4. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE3

  5. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE3

Show 4 earlier versions
  1. Jul 2025 — Aug 2025 [monthly]

    Recruiting PHASE3

  2. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE3

  3. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE3

  4. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE3

    First recorded

Feb 2025

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Adverum Biotechnologies, Inc.
Data source: Adverum Biotechnologies, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .