Completed PHASE3 INTERVENTIONAL 2-arm NCT01499277

Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections

A Phase III, Multicentre, Randomised, Double-Blind Comparative Study to Evaluate the Efficacy and Safety of Ceftaroline Fosamil (600 mg Every 8 Hours) Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Complicated Bacterial Skin and Soft Tissue Infections With Evidence of Systemic Inflammatory Response or Underlying Comorbidities

Sponsor: Forest Laboratories

Conditions Complicated Skin and Soft Tissue Infection

Interventions Aztreonam Ceftaroline fosamil Vancomycin

Updated 8 times since 2017 Last updated: Sep 1, 2017 Started: May 31, 2012 Primary completion: Jun 30, 2014 Completion: Jan 31, 2015

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Complicated Skin and Soft Tissue Infection and is currently completed. Forest Laboratories leads this study, which shows 8 recorded versions since 2012 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 3 earlier versions

Oct 2017 — Jun 2018 [monthly]

Completed PHASE3
Feb 2017 — Oct 2017 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

May 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Forest Laboratories
Pfizer

Data source: Pfizer

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Ankara, Turkey (Türkiye) , Ansan, South Korea , Athens, Greece , Barcelona, Spain , Beijing, China , Bellaire, United States , Belo Horizonte, Brazil , Benoni, South Africa , Brussels, Belgium , Bucharest, Romania and 81 more locations