deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 2-arm NCT01503632

Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission

A Comprehensive Approach to Improve Medication Adherence in Pediatric ALL

Sponsor: Children's Oncology Group

Conditions Acute Lymphoblastic Leukemia
Interventions Behavioral Intervention Compliance Monitoring Laboratory Biomarker Analysis Mercaptopurine Questionnaire Administration Standard Follow-Up Care
Updated 23 times since 2017 Last updated: Sep 16, 2025 Started: Feb 21, 2012 Primary completion: Jun 30, 2019 Completion: Dec 31, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01503632, this PHASE3 trial focuses on Acute Lymphoblastic Leukemia and remains ongoing. Sponsored by Children's Oncology Group, it has been updated 23 times since 2012, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Oct 2017 · 8 months · monthly snapshot~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Dec 2018 · 3 months · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~May 2019 · 3 months · monthly snapshot~May 2019 – ~Aug 2019 · 3 months · monthly snapshot~Aug 2019 – ~Jan 2020 · 5 months · monthly snapshot~Jan 2020 – ~Aug 2020 · 7 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Feb 2022 · 4 months · monthly snapshot~Feb 2022 – ~Jun 2022 · 4 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2023 · 14 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – present · 9 months · monthly snapshot

Change History

23 versions recorded

  1. Oct 2025 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Sep 2024 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Sep 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

▶ Show 18 earlier versions

  1. Jul 2022 — Sep 2023 [monthly]

    Active Not Recruiting PHASE3

  2. Jun 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE3

  3. Feb 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE3

    Status: Completed → Active Not Recruiting

  4. Oct 2021 — Feb 2022 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

  5. Jan 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE3

  6. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  7. Aug 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE3

  8. Jan 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE3

  9. Aug 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE3

  10. May 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE3

  11. Feb 2019 — May 2019 [monthly]

    Active Not Recruiting PHASE3

  12. Dec 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  13. Sep 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  14. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE3

  15. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

  16. Oct 2017 — Jun 2018 [monthly]

    Recruiting PHASE3

  17. Feb 2017 — Oct 2017 [monthly]

    Recruiting PHASE3

  18. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Feb 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Oncology Group
  • National Cancer Institute (NCI)
Data source: Children's Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Akron, United States , Albany, United States , Albuquerque, United States , Ann Arbor, United States , Asheville, United States , Atlanta, United States , Austin, United States , Birmingham, United States , Charlotte, United States , Chicago, United States and 70 more locations