deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT01536054

Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer

A Phase I Clinical Trial of mTOR Inhibition With Sirolimus for Enhancing ALVAC(2)-NY-ESO-1(M)/TRICOM Vaccine Induced Anti-Tumor Immunity in Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

Sponsor: National Cancer Institute (NCI)

Updated 14 times since 2017 Last updated: Mar 25, 2020 Started: Aug 20, 2012 Primary completion: Apr 21, 2015 Completion: Apr 21, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Recurrent Fallopian Tube Cancer and Recurrent Ovarian Epithelial Cancer and is currently completed. National Cancer Institute (NCI) leads this study, which shows 14 recorded versions since 2012 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshot~Apr 2017 – ~Jun 2018 · 14 months · monthly snapshot~Jun 2018 – ~Jan 2019 · 7 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~Jul 2019 · 3 months · monthly snapshot~Jul 2019 – ~Sep 2019 · 2 months · monthly snapshot~Sep 2019 – ~Jan 2020 · 4 months · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 21 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Apr 2020 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  5. Jan 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE1

Show 9 earlier versions
  1. Sep 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE1

  2. Jul 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE1

  3. Apr 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE1

  4. Feb 2019 — Apr 2019 [monthly]

    Active Not Recruiting PHASE1

  5. Jan 2019 — Feb 2019 [monthly]

    Active Not Recruiting PHASE1

  6. Jun 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE1

  7. Apr 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

  8. Feb 2017 — Apr 2017 [monthly]

    Active Not Recruiting PHASE1

  9. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1

    First recorded

Aug 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • Roswell Park Cancer Institute
  • Sanofi Pasteur, a Sanofi Company
Data source: Roswell Park Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations