A Safety and Tolerability Study of Assisted and Self-Administered Subcutaneous (SC) Herceptin (Trastuzumab) as Adjuvant Therapy in Early Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer (SafeHER)
A Phase III Prospective, Two-Cohort Non-Randomized, Multi-Centre, Multinational, Open-Label Study to Assess the Safety of Assisted- and Self-Administered Subcutaneous Trastuzumab as Therapy in Patients With Operable HER2-Positive Early Breast Cancer
Sponsor: Hoffmann-La Roche
A PHASE3 clinical study on Breast Neoplasms, this trial is completed. The trial is conducted by Hoffmann-La Roche and has accumulated 24 data snapshots since 2012. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.
Status Flow
Change History
24 versions recorded-
Dec 2025 — Present [monthly]
Completed PHASE3
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Nov 2025 — Dec 2025 [monthly]
Completed PHASE3
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Sep 2025 — Nov 2025 [monthly]
Completed PHASE3
-
Sep 2024 — Sep 2025 [monthly]
Completed PHASE3
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Jul 2024 — Sep 2024 [monthly]
Completed PHASE3
▶ Show 19 earlier versions
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May 2021 — Jul 2024 [monthly]
Completed PHASE3
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Feb 2021 — May 2021 [monthly]
Completed PHASE3
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Jan 2021 — Feb 2021 [monthly]
Completed PHASE3
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Aug 2020 — Jan 2021 [monthly]
Completed PHASE3
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Jun 2020 — Aug 2020 [monthly]
Completed PHASE3
Status: Active Not Recruiting → Completed
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Apr 2020 — Jun 2020 [monthly]
Active Not Recruiting PHASE3
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Dec 2019 — Apr 2020 [monthly]
Active Not Recruiting PHASE3
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Sep 2019 — Dec 2019 [monthly]
Active Not Recruiting PHASE3
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Jul 2019 — Sep 2019 [monthly]
Active Not Recruiting PHASE3
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Apr 2019 — Jul 2019 [monthly]
Active Not Recruiting PHASE3
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Jan 2019 — Apr 2019 [monthly]
Active Not Recruiting PHASE3
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Oct 2018 — Jan 2019 [monthly]
Active Not Recruiting PHASE3
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Jul 2018 — Oct 2018 [monthly]
Active Not Recruiting PHASE3
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Jun 2018 — Jul 2018 [monthly]
Active Not Recruiting PHASE3
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May 2018 — Jun 2018 [monthly]
Active Not Recruiting PHASE3
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Jan 2018 — May 2018 [monthly]
Active Not Recruiting PHASE3
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Jun 2017 — Jan 2018 [monthly]
Active Not Recruiting PHASE3
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Feb 2017 — Jun 2017 [monthly]
Active Not Recruiting PHASE3
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Jan 2017 — Feb 2017 [monthly]
Active Not Recruiting PHASE3
First recorded
May 2012
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Hoffmann-La Roche
For direct contact, visit the study record on ClinicalTrials.gov .