deltatrials
Completed PHASE2 INTERVENTIONAL 3-arm NCT01660451

Open-label, Uncontrolled Phase II Trial of Intravenous PI3K Inhibitor BAY80-6946 in Patients With Relapsed, Indolent or Aggressive Non-Hodgkin's Lymphomas

Sponsor: Bayer

Conditions Lymphoma, Non-Hodgkin
Interventions Copanlisib (Aliqopa, BAY80-6946)
Updated 60 times since 2017 Last updated: Jun 25, 2024 Started: Nov 19, 2012 Primary completion: Jun 22, 2016 Completion: May 18, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01660451, this PHASE2 trial focuses on Lymphoma, Non-Hodgkin and remains completed. Sponsored by Bayer, it has been updated 60 times since 2012, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Oct 2017 · 4 months · monthly snapshot~Oct 2017 – ~Jan 2018 · 3 months · monthly snapshot~Jan 2018 – ~Mar 2018 · 59 days · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Jan 2022 · 2 months · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~May 2022 · 2 months · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jul 2023 · 2 months · monthly snapshot~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

60 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jul 2024 — Aug 2024 [monthly]

    Completed PHASE2

  5. Jul 2023 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

▶ Show 55 earlier versions

  1. May 2023 — Jul 2023 [monthly]

    Active Not Recruiting PHASE2

  2. Apr 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE2

  3. Feb 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE2

  4. Jan 2023 — Feb 2023 [monthly]

    Active Not Recruiting PHASE2

  5. Dec 2022 — Jan 2023 [monthly]

    Active Not Recruiting PHASE2

  6. Nov 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE2

  7. Sep 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE2

  8. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2

  9. Jun 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE2

  10. May 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE2

  11. Mar 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE2

  12. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE2

  13. Jan 2022 — Feb 2022 [monthly]

    Active Not Recruiting PHASE2

  14. Nov 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE2

  15. Oct 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE2

  16. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE2

  17. May 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  18. Apr 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE2

  19. Mar 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE2

  20. Feb 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE2

  21. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE2

  22. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  23. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE2

  24. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE2

  25. Sep 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE2

  26. Aug 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE2

  27. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2

  28. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE2

  29. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE2

  30. Apr 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE2

  31. Mar 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE2

  32. Feb 2020 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2

  33. Jan 2020 — Feb 2020 [monthly]

    Active Not Recruiting PHASE2

  34. Nov 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE2

  35. Oct 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE2

  36. Sep 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE2

  37. Aug 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE2

  38. Jun 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE2

  39. May 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE2

  40. Apr 2019 — May 2019 [monthly]

    Active Not Recruiting PHASE2

  41. Mar 2019 — Apr 2019 [monthly]

    Active Not Recruiting PHASE2

  42. Feb 2019 — Mar 2019 [monthly]

    Active Not Recruiting PHASE2

  43. Dec 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE2

  44. Nov 2018 — Dec 2018 [monthly]

    Active Not Recruiting PHASE2

  45. Oct 2018 — Nov 2018 [monthly]

    Active Not Recruiting PHASE2

  46. Sep 2018 — Oct 2018 [monthly]

    Active Not Recruiting PHASE2

  47. Aug 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE2

  48. Jul 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE2

  49. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE2

  50. Mar 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  51. Jan 2018 — Mar 2018 [monthly]

    Active Not Recruiting PHASE2

  52. Oct 2017 — Jan 2018 [monthly]

    Active Not Recruiting PHASE2

  53. Jun 2017 — Oct 2017 [monthly]

    Active Not Recruiting PHASE2

  54. Feb 2017 — Jun 2017 [monthly]

    Active Not Recruiting PHASE2

  55. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Nov 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bayer
Data source: Bayer

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Anaheim, United States , Ankara, Turkey (Türkiye) , Athens, Greece , Aurora, United States , Barcelona, Spain , Berlin, Germany , Birmingham, United Kingdom , Birmingham, United States , Bologna, Italy , Brescia, Italy and 85 more locations