deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT01702064

Ruxolitinib in Combination With Nilotinib in Chronic Myeloid Leukemia (CML) Patients

A Phase I Study of Ruxolitinib in Combination With Nilotinib in CML Patients With Evidence of Molecular Disease

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Conditions Chronic Phase Chronic Myeloid Leukemia
Interventions Nilotinib Ruxolitinib
Updated 15 times since 2017 Last updated: Jan 4, 2021 Started: Feb 21, 2013 Primary completion: Oct 17, 2016 Completion: Jan 9, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01702064, this PHASE1 trial focuses on Chronic Phase Chronic Myeloid Leukemia and remains completed. Sponsored by H. Lee Moffitt Cancer Center and Research Institute, it has been updated 15 times since 2013, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Sep 2017 · 7 months · monthly snapshot~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Dec 2018 · 5 months · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~May 2019 · 3 months · monthly snapshot~May 2019 – ~Oct 2019 · 5 months · monthly snapshot~Oct 2019 – ~Apr 2020 · 6 months · monthly snapshot~Apr 2020 – ~Sep 2020 · 5 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Jul 2024 · 41 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 24 months · monthly snapshot

Change History

15 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Feb 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Jan 2021 — Feb 2021 [monthly]

    Completed PHASE1

  5. Sep 2020 — Jan 2021 [monthly]

    Completed PHASE1

▶ Show 10 earlier versions

  1. Apr 2020 — Sep 2020 [monthly]

    Completed PHASE1

  2. Oct 2019 — Apr 2020 [monthly]

    Completed PHASE1

  3. May 2019 — Oct 2019 [monthly]

    Completed PHASE1

  4. Feb 2019 — May 2019 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  5. Dec 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE1

  6. Jul 2018 — Dec 2018 [monthly]

    Active Not Recruiting PHASE1

  7. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE1

  8. Sep 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

  9. Feb 2017 — Sep 2017 [monthly]

    Active Not Recruiting PHASE1

  10. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1

    First recorded

Feb 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • H. Lee Moffitt Cancer Center and Research Institute
  • Incyte Corporation
Data source: H. Lee Moffitt Cancer Center and Research Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations