deltatrials
Terminated PHASE3 INTERVENTIONAL 5-arm NCT01764997

An Evaluation of Sarilumab Plus Methotrexate Compared to Etanercept Plus Methotrexate in RA Patients Not Responding to Adalimumab Plus Methotrexate (RA-COMPARE)

A Randomized, Controlled Study of Sarilumab and Methotrexate (MTX) Versus Etanercept and MTX in Patients With Rheumatoid Arthritis (RA) and an Inadequate Response to 4 Months of Treatment With Adalimumab and MTX

Sponsor: Regeneron Pharmaceuticals

Updated 10 times since 2017 Last updated: Jun 28, 2017 Started: Apr 30, 2013 Primary completion: Jan 31, 2015 Completion: Jan 31, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Due to small number of participants entering randomization. Not a safety issue.

A PHASE3 clinical study on Rheumatoid Arthritis, this trial is terminated or withdrawn. The trial is conducted by Regeneron Pharmaceuticals and has accumulated 10 data snapshots since 2013. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshotTerminated~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshotTerminated~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshotTerminated~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 8 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE3

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE3

Show 5 earlier versions
  1. Jun 2018 — Jan 2021 [monthly]

    Terminated PHASE3

  2. Sep 2017 — Jun 2018 [monthly]

    Terminated PHASE3

  3. Aug 2017 — Sep 2017 [monthly]

    Terminated PHASE3

  4. Feb 2017 — Aug 2017 [monthly]

    Terminated PHASE3

  5. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE3

    First recorded

Apr 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Regeneron Pharmaceuticals
  • Sanofi
Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .