deltatrials
Completed PHASE3 INTERVENTIONAL 1-arm NCT01844232

One Year, Open Label, Dose Escalation Long-term Safety Study in Multiple Sclerosis (MS) Subjects With Spasticity

A One Year, Open Label, Dose Escalation Study To Evaluate the Long-Term Safety of Arbaclofen Extended Release Tablets (AERT) in Multiple Sclerosis Subjects With Spasticity

Sponsor: Osmotica Pharmaceutical US LLC

Interventions arbaclofen
Updated 11 times since 2017 Last updated: Apr 21, 2022 Started: Apr 30, 2013 Primary completion: Dec 31, 2014 Completion: Jan 31, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Multiple Sclerosis and Spasticity and is currently completed. Osmotica Pharmaceutical US LLC leads this study, which shows 11 recorded versions since 2013 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~Feb 2020 · 20 months · monthly snapshotCompleted~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshotCompleted~Jan 2021 – ~Apr 2022 · 15 months · monthly snapshotCompleted~Apr 2022 – ~May 2022 · 30 days · monthly snapshotCompleted~May 2022 – ~Jul 2024 · 26 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshotCompleted~Dec 2025 – present · 9 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Dec 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2025 — Dec 2025 [monthly]

    Completed PHASE3

  3. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  5. May 2022 — Jul 2024 [monthly]

    Completed PHASE3

Show 6 earlier versions
  1. Apr 2022 — May 2022 [monthly]

    Completed PHASE3

  2. Jan 2021 — Apr 2022 [monthly]

    Completed PHASE3

  3. Feb 2020 — Jan 2021 [monthly]

    Completed PHASE3

  4. Jun 2018 — Feb 2020 [monthly]

    Completed PHASE3

  5. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE3

  6. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Apr 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Osmotica Pharmaceutical US LLC
  • RVL Pharmaceuticals, Inc.
Data source: RVL Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .