deltatrials
Completed PHASE3 INTERVENTIONAL 3-arm NCT03290131

A Study to Investigate the Safety and Effectiveness of Arbaclofen Extended-Release Tablets for Patients With MS (OS440-3004)

A Randomized, Double-Blind, Placebo-Controlled Parallel Group Study to Investigate the Safety and Efficacy of Arbaclofen Extended-Release Tablets for the Treatment of Spasticity in Patients With Multiple Sclerosis

Sponsor: Osmotica Pharmaceutical US LLC

Updated 12 times since 2017 Last updated: Jul 12, 2022 Started: Jan 28, 2018 Primary completion: Dec 3, 2018 Completion: Jan 2, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Multiple Sclerosis and Spasticity, Muscle, this trial is completed. The trial is conducted by Osmotica Pharmaceutical US LLC and has accumulated 12 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Oct 2017 – ~Mar 2018 · 5 months · monthly snapshotNot Yet Recruiting~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshotRecruiting~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshotRecruiting~Feb 2019 – ~Oct 2019 · 8 months · monthly snapshotActive Not Recruiting~Oct 2019 – ~Jan 2021 · 15 months · monthly snapshotCompleted~Jan 2021 – ~Apr 2022 · 15 months · monthly snapshotCompleted~Apr 2022 – ~Jun 2022 · 2 months · monthly snapshotCompleted~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshotCompleted~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Sep 2022 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2022 — Sep 2022 [monthly]

    Completed PHASE3

Show 7 earlier versions
  1. Apr 2022 — Jun 2022 [monthly]

    Completed PHASE3

  2. Jan 2021 — Apr 2022 [monthly]

    Completed PHASE3

  3. Oct 2019 — Jan 2021 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  4. Feb 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  5. Jun 2018 — Feb 2019 [monthly]

    Recruiting PHASE3

  6. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  7. Oct 2017 — Mar 2018 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Osmotica Pharmaceutical US LLC
  • RVL Pharmaceuticals, Inc.
Data source: RVL Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .