deltatrials
Active Not Recruiting OBSERVATIONAL NCT01848561

A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC) (LEGACY)

A Long-Term Non-Interventional Postmarketing Study to Assess Safety and Effectiveness of HUMIRA® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)

Sponsor: AbbVie

Conditions Ulcerative Colitis (UC)
Updated 24 times since 2017 Last updated: Jul 14, 2025 Started: Apr 29, 2013 Primary completion: Jun 30, 2028 Completion: Jun 30, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Ulcerative Colitis (UC) and is currently ongoing. AbbVie leads this study, which shows 24 recorded versions since 2013 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Sep 2017 · 4 months · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Mar 2018 · 5 months · monthly snapshot~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Apr 2019 · 3 months · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Oct 2019 · 4 months · monthly snapshot~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~Aug 2020 · 4 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Feb 2022 · 12 months · monthly snapshot~Feb 2022 – ~Jul 2023 · 17 months · monthly snapshot~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

24 versions recorded

  1. Sep 2025 — Present [monthly]

    Active Not Recruiting

  2. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting

  3. Sep 2024 — Aug 2025 [monthly]

    Active Not Recruiting

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting

  5. Jul 2023 — Jul 2024 [monthly]

    Active Not Recruiting

▶ Show 19 earlier versions

  1. Feb 2022 — Jul 2023 [monthly]

    Active Not Recruiting

  2. Feb 2021 — Feb 2022 [monthly]

    Active Not Recruiting

  3. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting

  4. Aug 2020 — Jan 2021 [monthly]

    Active Not Recruiting

    Status: Recruiting → Active Not Recruiting

  5. Apr 2020 — Aug 2020 [monthly]

    Recruiting

  6. Jan 2020 — Apr 2020 [monthly]

    Recruiting

  7. Oct 2019 — Jan 2020 [monthly]

    Recruiting

  8. Jun 2019 — Oct 2019 [monthly]

    Recruiting

  9. Apr 2019 — Jun 2019 [monthly]

    Recruiting

  10. Jan 2019 — Apr 2019 [monthly]

    Recruiting

  11. Nov 2018 — Jan 2019 [monthly]

    Recruiting

  12. Jun 2018 — Nov 2018 [monthly]

    Recruiting

  13. Apr 2018 — Jun 2018 [monthly]

    Recruiting

    Phase: NA → None

  14. Mar 2018 — Apr 2018 [monthly]

    Recruiting NA

  15. Oct 2017 — Mar 2018 [monthly]

    Recruiting NA

  16. Sep 2017 — Oct 2017 [monthly]

    Recruiting NA

  17. May 2017 — Sep 2017 [monthly]

    Recruiting NA

  18. Feb 2017 — May 2017 [monthly]

    Recruiting NA

  19. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

Apr 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AbbVie
Data source: AbbVie

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

A Coruña, Spain , Aalborg, Denmark , Aalst, Belgium , Abbotstown, Ireland , Adelaide, Australia , Alcalá de Henares, Spain , Alcorcón, Spain , Alcázar de San Juan, Spain , Alexandroupoli, Greece , Alicante, Spain and 384 more locations