deltatrials
Terminated PHASE1 INTERVENTIONAL 2-arm NCT01948297

Debio 1347-101 Phase I Trial in Advanced Solid Tumours With Fibroblast Growth Factor Receptor (FGFR) Alterations

A Phase I, Gene Alteration-based, Open Label, Multicenter Study of Oral Debio 1347 (CH5183284) in Patients With Advanced Solid Malignancies, Whose Tumours Have an Alteration of the FGFR 1, 2 or 3 Genes

Sponsor: Debiopharm International SA

Conditions Solid Tumours
Interventions Debio1347 (CH5183284)
Updated 37 times since 2017 Last updated: Sep 8, 2020 Started: Aug 31, 2013 Primary completion: Jun 26, 2020 Completion: Jun 26, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This trial was terminated. No reason was provided.

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A PHASE1 clinical study on Solid Tumours, this trial is terminated or withdrawn. The trial is conducted by Debiopharm International SA and has accumulated 37 data snapshots since 2013. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Jul 2017 · 2 months · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

37 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  4. Jan 2021 — Jul 2024 [monthly]

    Terminated PHASE1

  5. Oct 2020 — Jan 2021 [monthly]

    Terminated PHASE1

    Status: Active Not Recruiting → Terminated

▶ Show 32 earlier versions

  1. Sep 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE1

  2. Aug 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE1

  3. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE1

  4. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE1

  5. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE1

  6. Apr 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  7. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE1

  8. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE1

  9. Dec 2019 — Feb 2020 [monthly]

    Recruiting PHASE1

  10. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE1

  11. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE1

  12. Aug 2019 — Oct 2019 [monthly]

    Recruiting PHASE1

  13. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE1

  14. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE1

  15. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE1

  16. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE1

  17. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE1

  18. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE1

  19. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE1

  20. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE1

  21. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE1

  22. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE1

  23. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE1

  24. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE1

  25. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE1

  26. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE1

  27. Sep 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

    Status: Active Not Recruiting → Recruiting

  28. Aug 2017 — Sep 2017 [monthly]

    Active Not Recruiting PHASE1

  29. Jul 2017 — Aug 2017 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  30. May 2017 — Jul 2017 [monthly]

    Recruiting PHASE1

  31. Feb 2017 — May 2017 [monthly]

    Recruiting PHASE1

  32. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Aug 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Debiopharm International SA
Data source: Debiopharm International SA

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations