deltatrials
Terminated PHASE1 INTERVENTIONAL 3-arm NCT03968653

Study of Oral Debio 0123 in Combination With Carboplatin in Participants With Advanced Solid Tumors

A Phase 1 Study of Oral Debio 0123 in Combination With Carboplatin in Patients With Advanced Solid Tumors

Sponsor: Debiopharm International SA

Conditions Advanced Solid Tumors
Interventions Carboplatin Debio 0123
Updated 63 times since 2019 Last updated: Nov 28, 2025 Started: Jul 30, 2019 Primary completion: Oct 23, 2025 Completion: Oct 23, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This trial was concluded for strategic reasons.

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A PHASE1 clinical study on Advanced Solid Tumors, this trial is terminated or withdrawn. The trial is conducted by Debiopharm International SA and has accumulated 63 data snapshots since 2019. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Oct 2019 · 3 months · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Dec 2020 · 2 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Jun 2022 · 4 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Oct 2022 · 30 days · monthly snapshot~Oct 2022 – ~Nov 2022 · 31 days · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Nov 2023 · 2 months · monthly snapshot~Nov 2023 – ~Jan 2024 · 2 months · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~May 2025 · 2 months · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – ~Jan 2026 · 2 months · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

63 versions recorded

  1. Jan 2026 — Present [monthly]

    Terminated PHASE1

    Status: Active Not Recruiting → Terminated

  2. Nov 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE1

  3. Sep 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE1

  4. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE1

  5. Jul 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE1

▶ Show 58 earlier versions

  1. Jun 2025 — Jul 2025 [monthly]

    Active Not Recruiting PHASE1

  2. May 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Mar 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  4. Feb 2025 — Mar 2025 [monthly]

    Recruiting PHASE1

  5. Jan 2025 — Feb 2025 [monthly]

    Recruiting PHASE1

  6. Dec 2024 — Jan 2025 [monthly]

    Recruiting PHASE1

  7. Nov 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

  8. Sep 2024 — Nov 2024 [monthly]

    Recruiting PHASE1

  9. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  10. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

  11. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  12. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE1

  13. Apr 2024 — May 2024 [monthly]

    Recruiting PHASE1

  14. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE1

  15. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE1

  16. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE1

  17. Nov 2023 — Jan 2024 [monthly]

    Recruiting PHASE1

  18. Sep 2023 — Nov 2023 [monthly]

    Recruiting PHASE1

  19. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE1

  20. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE1

  21. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE1

  22. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE1

  23. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE1

  24. Feb 2023 — Apr 2023 [monthly]

    Recruiting PHASE1

  25. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE1

  26. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE1

  27. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE1

  28. Oct 2022 — Nov 2022 [monthly]

    Recruiting PHASE1

  29. Sep 2022 — Oct 2022 [monthly]

    Recruiting PHASE1

  30. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  31. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE1

  32. Feb 2022 — Jun 2022 [monthly]

    Recruiting PHASE1

  33. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE1

  34. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE1

  35. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE1

  36. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE1

  37. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE1

  38. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  39. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE1

  40. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE1

  41. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE1

  42. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE1

  43. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  44. Oct 2020 — Dec 2020 [monthly]

    Recruiting PHASE1

  45. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE1

  46. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE1

  47. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE1

  48. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE1

  49. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE1

  50. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE1

  51. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE1

  52. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE1

  53. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE1

  54. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE1

  55. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE1

  56. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  57. Jul 2019 — Oct 2019 [monthly]

    Not Yet Recruiting PHASE1

  58. Jun 2019 — Jul 2019 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Debiopharm International SA
Data source: Debiopharm International SA

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations