deltatrials
Completed PHASE1 INTERVENTIONAL 3-arm NCT02006485

Ublituximab in Combination With TGR-1202 +/- Ibrutinib or Bendamustine in Patients With B-cell Malignancies

A Phase I/Ib Study Evaluating the Efficacy and Safety of Ublituximab, a Third-Generation Anti-CD20 Monoclonal Antibody, in Combination With TGR-1202, a Novel PI3k Delta Inhibitor; and Ibrutinib or Bendamustine, in Patients With B-cell Malignancies.

Sponsor: TG Therapeutics, Inc.

Updated 11 times since 2017 Last updated: Nov 4, 2019 Started: Dec 13, 2013 Primary completion: Oct 31, 2019 Completion: Oct 31, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Chronic Lymphocytic Leukemia and Non-Hodgkin's Lymphoma, this trial is completed. The trial is conducted by TG Therapeutics, Inc. and has accumulated 11 data snapshots since 2013. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotRecruiting~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshotRecruiting~Oct 2018 – ~Sep 2019 · 11 months · monthly snapshotActive Not Recruiting~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshotActive Not Recruiting~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshotActive Not Recruiting~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshotCompleted~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Dec 2019 — Jan 2021 [monthly]

    Completed PHASE1

  5. Nov 2019 — Dec 2019 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 6 earlier versions
  1. Oct 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE1

  2. Sep 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE1

  3. Oct 2018 — Sep 2019 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. Jun 2018 — Oct 2018 [monthly]

    Recruiting PHASE1

  5. Feb 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

  6. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Dec 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • TG Therapeutics, Inc.
Data source: TG Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .