deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT02007252

ACZ885 for the Treatment of Abdominal Aortic Aneurysm (AAA)

A Randomized, Double-blind, Placebo-controlled, Multiple Dose Study of Subcutaneous ACZ885 for the Treatment of Abdominal Aortic Aneurysm

Sponsor: Novartis Pharmaceuticals

Interventions ACZ885 Placebo
Updated 13 times since 2017 Last updated: Dec 9, 2020 Started: Dec 31, 2013 Primary completion: Oct 31, 2015 Completion: Oct 31, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The results of a third interim analysis (ad hoc) indicated a lack of efficacy and futility in continuing the trial.

This PHASE2 trial investigates Abdominal Aortic Aneurysm (AAA) and is currently terminated or withdrawn. Novartis Pharmaceuticals leads this study, which shows 13 recorded versions since 2013 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshot~Aug 2017 – ~May 2018 · 9 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~May 2019 · 11 months · monthly snapshot~May 2019 – ~Nov 2020 · 18 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Dec 2021 · 10 months · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Feb 2021 — Dec 2021 [monthly]

    Terminated PHASE2

Show 8 earlier versions
  1. Jan 2021 — Feb 2021 [monthly]

    Terminated PHASE2

  2. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE2

  3. May 2019 — Nov 2020 [monthly]

    Terminated PHASE2

  4. Jun 2018 — May 2019 [monthly]

    Terminated PHASE2

  5. May 2018 — Jun 2018 [monthly]

    Terminated PHASE2

  6. Aug 2017 — May 2018 [monthly]

    Terminated PHASE2

  7. Feb 2017 — Aug 2017 [monthly]

    Terminated PHASE2

  8. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE2

    First recorded

Dec 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .