deltatrials
Completed PHASE2 INTERVENTIONAL 4-arm NCT02015520

Phase IIB Dose Ranging Study in Subjects With Moderate to Severe Rheumatoid Arthritis

A Phase IIb, Randomized, Multi-Center, Double-Blind, Dose-Ranging Study to Evaluate the Efficacy and Safety of Clazakizumab in Subjects With Moderate to Severe Active Rheumatoid Arthritis Who Have Experienced an Inadequate Response to TNF Inhibitors

Sponsor: CSL Behring

Updated 12 times since 2017 Last updated: Apr 16, 2021 Started: Jun 30, 2012 Primary completion: Jun 30, 2013 Completion: Jun 30, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Rheumatoid Arthritis and is currently completed. CSL Behring leads this study, which shows 12 recorded versions since 2012 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Oct 2017 · 8 months · monthly snapshotCompleted~Oct 2017 – ~May 2018 · 7 months · monthly snapshotCompleted~May 2018 – ~Jun 2018 · 31 days · monthly snapshotCompleted~Jun 2018 – ~Aug 2020 · 26 months · monthly snapshotCompleted~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotCompleted~Jan 2021 – ~May 2021 · 4 months · monthly snapshotCompleted~May 2021 – ~Jun 2021 · 31 days · monthly snapshotCompleted~Jun 2021 – ~Jul 2024 · 37 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jun 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. May 2021 — Jun 2021 [monthly]

    Completed PHASE2

Show 7 earlier versions
  1. Jan 2021 — May 2021 [monthly]

    Completed PHASE2

  2. Aug 2020 — Jan 2021 [monthly]

    Completed PHASE2

  3. Jun 2018 — Aug 2020 [monthly]

    Completed PHASE2

  4. May 2018 — Jun 2018 [monthly]

    Completed PHASE2

  5. Oct 2017 — May 2018 [monthly]

    Completed PHASE2

  6. Feb 2017 — Oct 2017 [monthly]

    Completed PHASE2

  7. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2

    First recorded

Jun 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • CSL Behring
Data source: CSL Behring

For direct contact, visit the study record on ClinicalTrials.gov .