Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients (IMAGINE)
A Pivotal Phase 3 Trial to Evaluate the Safety and Efficacy of Clazakizumab for the Treatment of Chronic Active Antibody-mediated Rejection in Kidney Transplant Recipients
Sponsor: CSL Behring
Terminated
Early stop for lack of efficacy/futility (at Interim analysis)
Other terminated trials from CSL Behring
Other Antibody-mediated Rejection trials with similar outcome
A PHASE3 clinical study on Antibody-mediated Rejection, this trial is terminated or withdrawn. The trial is conducted by CSL Behring and has accumulated 32 data snapshots since 2019. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.
Status Flow
Change History
32 versions recorded-
Feb 2026 — Present [monthly]
Terminated PHASE3
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Sep 2025 — Feb 2026 [monthly]
Terminated PHASE3
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Aug 2025 — Sep 2025 [monthly]
Terminated PHASE3
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Sep 2024 — Aug 2025 [monthly]
Terminated PHASE3
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Jul 2024 — Sep 2024 [monthly]
Terminated PHASE3
▶ Show 27 earlier versions
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May 2024 — Jul 2024 [monthly]
Terminated PHASE3
Status: Active Not Recruiting → Terminated
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Feb 2024 — May 2024 [monthly]
Active Not Recruiting PHASE3
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Dec 2023 — Feb 2024 [monthly]
Active Not Recruiting PHASE3
Status: Recruiting → Active Not Recruiting
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Nov 2023 — Dec 2023 [monthly]
Recruiting PHASE3
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Sep 2023 — Nov 2023 [monthly]
Recruiting PHASE3
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Aug 2023 — Sep 2023 [monthly]
Recruiting PHASE3
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May 2023 — Aug 2023 [monthly]
Recruiting PHASE3
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Nov 2022 — May 2023 [monthly]
Recruiting PHASE3
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Sep 2022 — Nov 2022 [monthly]
Recruiting PHASE3
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Apr 2022 — Sep 2022 [monthly]
Recruiting PHASE3
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Mar 2021 — Apr 2022 [monthly]
Recruiting PHASE3
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Jan 2021 — Mar 2021 [monthly]
Recruiting PHASE3
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Dec 2020 — Jan 2021 [monthly]
Recruiting PHASE3
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Aug 2020 — Dec 2020 [monthly]
Recruiting PHASE3
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May 2020 — Aug 2020 [monthly]
Recruiting PHASE3
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Apr 2020 — May 2020 [monthly]
Recruiting PHASE3
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Mar 2020 — Apr 2020 [monthly]
Recruiting PHASE3
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Feb 2020 — Mar 2020 [monthly]
Recruiting PHASE3
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Jan 2020 — Feb 2020 [monthly]
Recruiting PHASE3
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Dec 2019 — Jan 2020 [monthly]
Recruiting PHASE3
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Nov 2019 — Dec 2019 [monthly]
Recruiting PHASE3
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Oct 2019 — Nov 2019 [monthly]
Recruiting PHASE3
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Sep 2019 — Oct 2019 [monthly]
Recruiting PHASE3
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Jul 2019 — Sep 2019 [monthly]
Recruiting PHASE3
Status: Not Yet Recruiting → Recruiting
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May 2019 — Jul 2019 [monthly]
Not Yet Recruiting PHASE3
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Jan 2019 — May 2019 [monthly]
Not Yet Recruiting PHASE3
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Dec 2018 — Jan 2019 [monthly]
Not Yet Recruiting PHASE3
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- CSL Behring
- ICON Clinical Research
For direct contact, visit the study record on ClinicalTrials.gov .