Completed PHASE3 INTERVENTIONAL 2-arm NCT02025621

Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass (LEVO-CTS)

A Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery Requiring Cardiopulmonary Bypass

Sponsor: Tenax Therapeutics, Inc.

Conditions Coronary Artery Bypass Grafting Low Cardiac Output Syndrome Mitral Valve Surgery

Interventions Levosimendan Placebo

Updated 8 times since 2017 Last updated: May 22, 2018 Started: Jul 31, 2014 Primary completion: Nov 30, 2016 Completion: Nov 30, 2016

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Coronary Artery Bypass Grafting and Low Cardiac Output Syndrome and is currently completed. Tenax Therapeutics, Inc. leads this study, which shows 8 recorded versions since 2014 — indicating limited longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jul 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 3 earlier versions

Jun 2018 — Jul 2018 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Jul 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Tenax Therapeutics, Inc.

Data source: Tenax Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albany, United States , Allentown, United States , Ann Arbor, United States , Asheville, United States , Boca Raton, United States , Boston, United States , Burlington, United States , Charlottesville, United States , Cincinnati, United States , Cleveland, United States and 43 more locations