Completed PHASE1 INTERVENTIONAL 2-arm NCT02028689

Metformin and Furosemide Drug-Drug Interaction Study

A Phase 1, Randomized, Open-Label, Single-Dose Study to Evaluate Potential Pharmacokinetic Interaction Between Lesinurad and Metformin and Between Lesinurad and Furosemide in Health Adult Male Subjects

Sponsor: Ardea Biosciences, Inc.

Conditions Healthy

Interventions Furosemide 40 mg Lesinurad 400 mg Metformin 850 mg

Updated 6 times since 2017 Last updated: Feb 13, 2014 Started: Oct 31, 2013 Primary completion: Nov 30, 2013 Completion: Jan 31, 2014

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02028689, this PHASE1 trial focuses on Healthy and remains completed. Sponsored by Ardea Biosciences, Inc., it has been updated 6 times since 2013, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

6 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE1
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1
Jun 2018 — Jan 2021 [monthly]

Completed PHASE1
Feb 2017 — Jun 2018 [monthly]

Completed PHASE1

▶ Show 1 earlier version

Jan 2017 — Feb 2017 [monthly]

Completed PHASE1

First recorded

Oct 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Ardea Biosciences, Inc.

Data source: Ardea Biosciences, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Kalamazoo, United States