deltatrials
Completed PHASE1 INTERVENTIONAL 3-arm NCT02045602

Phase I Dose Escalation Study of Intravenous VCN-01 With or Without Gemcitabine and Abraxane® in Patients With Advanced Solid Tumors

A Phase I, Multicenter, Open-label, Dose Escalation Study of Intravenous Administration of VCN-01 Oncolytic Adenovirus With or Without Gemcitabine and Abraxane® in Patients With Advanced Solid Tumors

Sponsor: Theriva Biologics SL

Updated 14 times since 2017 Last updated: Oct 7, 2020 Started: Jan 31, 2014 Primary completion: May 31, 2019 Completion: Jan 31, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Locally Advanced Solid Tumors and Metastatic Solid Tumors, this trial is completed. The trial is conducted by Theriva Biologics SL and has accumulated 14 data snapshots since 2014. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshot~Aug 2017 – ~Feb 2018 · 6 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshot~Oct 2018 – ~Jun 2019 · 8 months · monthly snapshot~Jun 2019 – ~Oct 2019 · 4 months · monthly snapshot~Oct 2019 – ~Nov 2020 · 13 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2023 · 25 months · monthly snapshot~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Feb 2023 — Jul 2024 [monthly]

    Completed PHASE1

  5. Jan 2021 — Feb 2023 [monthly]

    Completed PHASE1

Show 9 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  2. Oct 2019 — Nov 2020 [monthly]

    Active Not Recruiting PHASE1

  3. Jun 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. Oct 2018 — Jun 2019 [monthly]

    Recruiting PHASE1

  5. Jun 2018 — Oct 2018 [monthly]

    Recruiting PHASE1

  6. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

  7. Aug 2017 — Feb 2018 [monthly]

    Recruiting PHASE1

  8. Feb 2017 — Aug 2017 [monthly]

    Recruiting PHASE1

  9. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Jan 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Theriva Biologics SL
Data source: Theriva Biologics SL

For direct contact, visit the study record on ClinicalTrials.gov .