deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 3-arm NCT05057715

huCART-meso + VCN-01 in Pancreatic and Ovarian Cancer

Phase 1 Trial of Human Chimeric Antigen Receptor Modified T Cells (huCART-meso) Administered in Combination With VCN-01 in Patients With Pancreatic and Serous Epithelial Ovarian Cancer

Sponsor: Theriva Biologics

Updated 12 times since 2021 Last updated: Jun 24, 2025 Started: Mar 2, 2022 Primary completion: Sep 30, 2038 Completion: Sep 30, 2038
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Pancreatic Cancer and Serous Ovarian Cancer and is currently ongoing. Theriva Biologics leads this study, which shows 12 recorded versions since 2022 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshotNot Yet Recruiting~Nov 2021 – ~Feb 2022 · 3 months · monthly snapshotNot Yet Recruiting~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshotNot Yet Recruiting~Apr 2022 – ~Feb 2023 · 10 months · monthly snapshotRecruiting~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshotRecruiting~Mar 2023 – ~Jun 2023 · 3 months · monthly snapshotRecruiting~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshotRecruiting~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshotRecruiting~Dec 2024 – ~Jul 2025 · 7 months · monthly snapshotActive Not Recruiting~Jul 2025 – present · 12 months · monthly snapshotActive Not Recruiting

Change History

12 versions recorded
  1. Jul 2025 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Dec 2024 — Jul 2025 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  3. Sep 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  5. Jul 2023 — Jul 2024 [monthly]

    Recruiting PHASE1

Show 7 earlier versions
  1. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE1

  2. Mar 2023 — Jun 2023 [monthly]

    Recruiting PHASE1

  3. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE1

  4. Apr 2022 — Feb 2023 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  5. Feb 2022 — Apr 2022 [monthly]

    Not Yet Recruiting PHASE1

  6. Nov 2021 — Feb 2022 [monthly]

    Not Yet Recruiting PHASE1

  7. Oct 2021 — Nov 2021 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Theriva Biologics
  • University of Pennsylvania
Data source: University of Pennsylvania

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations