deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT02046174

Open-Label Phase IIb Efficacy Trial of Cancer Macrobeads Compared to Best Supportive Care in Colorectal Cancer Patients

A Phase IIb, Nonrandomized, Open-Label Trial With Mouse Renal Adenocarcinoma (RENCA) Cell Containing Agarose-Agarose Macrobeads Compared With Best Supportive Care in Patients With Treatment-Resistant, Metastatic Colorectal Carcinoma

Sponsor: The Rogosin Institute

Conditions Colorectal Cancers
Interventions RENCA macrobeads
Updated 15 times since 2017 Last updated: Feb 25, 2021 Started: Apr 3, 2014 Primary completion: Oct 22, 2018 Completion: Oct 22, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Colorectal Cancers and is currently completed. The Rogosin Institute leads this study, which shows 15 recorded versions since 2014 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~May 2018 · 11 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshot~Feb 2019 – ~Jul 2019 · 5 months · monthly snapshot~Jul 2019 – ~Apr 2020 · 9 months · monthly snapshot~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Dec 2021 · 8 months · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

15 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Apr 2021 — Dec 2021 [monthly]

    Completed PHASE2

▶ Show 10 earlier versions

  1. Jan 2021 — Apr 2021 [monthly]

    Completed PHASE2

  2. Apr 2020 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  3. Jul 2019 — Apr 2020 [monthly]

    Active Not Recruiting PHASE2

  4. Feb 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE2

  5. Nov 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE2

  6. Jun 2018 — Nov 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  7. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  8. Jun 2017 — May 2018 [monthly]

    Recruiting PHASE2

  9. Feb 2017 — Jun 2017 [monthly]

    Recruiting PHASE2

  10. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Apr 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • The Rogosin Institute
  • Vital Systems Inc.
Data source: The Rogosin Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations