deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT02074436

PRevention Of BLeeding in hEmatological Malignancies With Antifibrinolytic (Epsilon Aminocaproic Acid) (PROBLEMA)

Randomized Trial of Epsilon Aminocaproic Acid Versus Platelet Transfusions for the Prevention of Bleeding in Thrombocytopenic Patients With Hematological Malignancies

Sponsor: Emory University

Updated 11 times since 2017 Last updated: Jun 26, 2022 Started: May 23, 2014 Primary completion: Nov 24, 2020 Completion: May 14, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Slow accrual

Listed as NCT02074436, this PHASE2 trial focuses on Hematological Malignancies and Thrombocytopenia and remains terminated or withdrawn. Sponsored by Emory University, it has been updated 11 times since 2014, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotRecruiting~Jun 2018 – ~Jun 2019 · 12 months · monthly snapshotRecruiting~Jun 2019 – ~Jun 2020 · 12 months · monthly snapshotRecruiting~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshotRecruiting~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshotRecruiting~Jun 2021 – ~Jun 2022 · 12 months · monthly snapshotRecruiting~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshotTerminated~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Sep 2022 — Jul 2024 [monthly]

    Terminated PHASE2

  4. Jun 2022 — Sep 2022 [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

  5. Jun 2021 — Jun 2022 [monthly]

    Recruiting PHASE2

Show 6 earlier versions
  1. Jan 2021 — Jun 2021 [monthly]

    Recruiting PHASE2

  2. Jun 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  3. Jun 2019 — Jun 2020 [monthly]

    Recruiting PHASE2

  4. Jun 2018 — Jun 2019 [monthly]

    Recruiting PHASE2

  5. Feb 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  6. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

May 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Emory University
Data source: Emory University

For direct contact, visit the study record on ClinicalTrials.gov .