deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT02199041

Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen

Sponsor: St. Jude Children's Research Hospital

Conditions Hematological Malignancies
Interventions CliniMACS Cyclophosphamide Fludarabine G-CSF Lymphocyte infusions Melphalan Mesna Methylprednisolone Mycophenolate mofetil Tacrolimus Thiotepa Total lymphoid irradiation
Updated 13 times since 2017 Last updated: Jan 10, 2018 Started: Jul 11, 2014 Primary completion: May 23, 2017 Completion: May 23, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was halted early due to slow accrual.

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Listed as NCT02199041, this PHASE2 trial focuses on Hematological Malignancies and remains terminated or withdrawn. Sponsored by St. Jude Children's Research Hospital, it has been updated 13 times since 2014, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshot~Apr 2017 – ~Jul 2017 · 3 months · monthly snapshot~Jul 2017 – ~Mar 2018 · 8 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Feb 2020 · 20 months · monthly snapshot~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Dec 2022 · 12 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

13 versions recorded

  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Terminated PHASE2

  5. Dec 2021 — Dec 2022 [monthly]

    Terminated PHASE2

▶ Show 8 earlier versions

  1. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE2

  2. Feb 2020 — Jan 2021 [monthly]

    Terminated PHASE2

  3. Jun 2018 — Feb 2020 [monthly]

    Terminated PHASE2

  4. Mar 2018 — Jun 2018 [monthly]

    Terminated PHASE2

  5. Jul 2017 — Mar 2018 [monthly]

    Terminated PHASE2

    Status: Recruiting → Terminated

  6. Apr 2017 — Jul 2017 [monthly]

    Recruiting PHASE2

  7. Feb 2017 — Apr 2017 [monthly]

    Recruiting PHASE2

  8. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Jul 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • St. Jude Children's Research Hospital
Data source: St. Jude Children's Research Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations