deltatrials
Completed PHASE4 INTERVENTIONAL 3-arm NCT02092467

Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis

PHASE 3B/4 RANDOMIZED SAFETY ENDPOINT STUDY OF 2 DOSES OF TOFACITINIB IN COMPARISON TO A TUMOR NECROSIS FACTOR (TNF) INHIBITOR IN SUBJECTS WITH RHEUMATOID ARTHRITIS

Sponsor: Pfizer

Conditions Arthritis, Rheumatoid
Interventions adalimumab etanercept tofacitinib
Updated 42 times since 2017 Last updated: Jul 21, 2021 Started: Mar 14, 2014 Primary completion: Jul 22, 2020 Completion: Jul 22, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Arthritis, Rheumatoid and is currently completed. Pfizer leads this study, which shows 42 recorded versions since 2014 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshot~Apr 2017 – ~May 2017 · 30 days · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Feb 2018 · 2 months · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshot~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Nov 2019 · 3 months · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~Jul 2020 · 3 months · monthly snapshot~Jul 2020 – ~Nov 2020 · 4 months · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Jul 2024 · 34 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – ~Feb 2026 · 2 months · monthly snapshot~Feb 2026 – present · 4 months · monthly snapshot

Change History

42 versions recorded

  1. Feb 2026 — Present [monthly]

    Completed PHASE4

  2. Dec 2025 — Feb 2026 [monthly]

    Completed PHASE4

  3. Sep 2025 — Dec 2025 [monthly]

    Completed PHASE4

  4. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE4

  5. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

▶ Show 37 earlier versions

  1. Sep 2021 — Jul 2024 [monthly]

    Completed PHASE4

  2. Jun 2021 — Sep 2021 [monthly]

    Completed PHASE4

  3. May 2021 — Jun 2021 [monthly]

    Completed PHASE4

  4. Apr 2021 — May 2021 [monthly]

    Completed PHASE4

  5. Mar 2021 — Apr 2021 [monthly]

    Completed PHASE4

  6. Jan 2021 — Mar 2021 [monthly]

    Completed PHASE4

  7. Dec 2020 — Jan 2021 [monthly]

    Completed PHASE4

  8. Nov 2020 — Dec 2020 [monthly]

    Completed PHASE4

    Status: Active Not Recruiting → Completed

  9. Jul 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE4

  10. Apr 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE4

  11. Jan 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE4

  12. Nov 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE4

  13. Aug 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE4

    Status: Recruiting → Active Not Recruiting

  14. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE4

  15. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE4

  16. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE4

  17. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE4

  18. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE4

  19. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE4

  20. Dec 2018 — Feb 2019 [monthly]

    Recruiting PHASE4

  21. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE4

  22. Sep 2018 — Nov 2018 [monthly]

    Recruiting PHASE4

  23. Jul 2018 — Sep 2018 [monthly]

    Recruiting PHASE4

  24. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE4

  25. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE4

  26. Mar 2018 — May 2018 [monthly]

    Recruiting PHASE4

  27. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE4

  28. Dec 2017 — Feb 2018 [monthly]

    Recruiting PHASE4

  29. Oct 2017 — Dec 2017 [monthly]

    Recruiting PHASE4

  30. Sep 2017 — Oct 2017 [monthly]

    Recruiting PHASE4

  31. Aug 2017 — Sep 2017 [monthly]

    Recruiting PHASE4

  32. Jul 2017 — Aug 2017 [monthly]

    Recruiting PHASE4

  33. Jun 2017 — Jul 2017 [monthly]

    Recruiting PHASE4

  34. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE4

  35. Apr 2017 — May 2017 [monthly]

    Recruiting PHASE4

  36. Feb 2017 — Apr 2017 [monthly]

    Recruiting PHASE4

  37. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE4

    First recorded

Mar 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Pfizer
Data source: Pfizer

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Amarillo, United States , Amman, Jordan , Ankara, Turkey (Türkiye) , Arequipa, Peru , Ashkelon, Israel , Atlanta, United States , Auckland, New Zealand , Austin, United States , Aydin, Turkey (Türkiye) , Bangkok, Thailand and 257 more locations