deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 2-arm NCT02112214

Helicobacter Pylori Eradication for Gastric Cancer Prevention in the General Population (HELPER)

Effect of Helicobacter Pylori Eradication on Gastric Cancer Prevention in Korea: a Randomized Controlled Clinical Trial

Sponsor: Chonnam National University Hospital

Conditions Gastric Cancer Helicobacter Pylori Infection
Interventions 10-day bismuth-based quadruple therapy Placebo
Updated 16 times since 2017 Last updated: Dec 25, 2024 Started: Jun 30, 2014 Primary completion: Dec 31, 2029 Completion: Dec 31, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Gastric Cancer and Helicobacter Pylori Infection, this trial is ongoing. The trial is conducted by Chonnam National University Hospital and has accumulated 16 data snapshots since 2014. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~May 2017 · 4 months · monthly snapshot~May 2017 – ~May 2018 · 12 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~Sep 2019 · 5 months · monthly snapshot~Sep 2019 – ~Feb 2020 · 5 months · monthly snapshot~Feb 2020 – ~Jul 2020 · 5 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Dec 2023 · 26 months · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~Sep 2025 · 8 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

16 versions recorded

  1. Sep 2025 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Jan 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Sep 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Dec 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

▶ Show 11 earlier versions

  1. Oct 2021 — Dec 2023 [monthly]

    Active Not Recruiting PHASE3

  2. Jan 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE3

  3. Jul 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  4. Feb 2020 — Jul 2020 [monthly]

    Recruiting PHASE3

  5. Sep 2019 — Feb 2020 [monthly]

    Recruiting PHASE3

  6. Apr 2019 — Sep 2019 [monthly]

    Recruiting PHASE3

  7. Feb 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  8. Jun 2018 — Feb 2019 [monthly]

    Recruiting PHASE3

  9. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  10. May 2017 — May 2018 [monthly]

    Recruiting PHASE3

  11. Jan 2017 — May 2017 [monthly]

    Recruiting PHASE3

    First recorded

Jun 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Chonnam National University Hospital
  • Chuncheon Sacred Heart Hospital
  • Chung-Ang University Hosptial, Chung-Ang University College of Medicine
  • Incheon St.Mary's Hospital/The Catholic University
  • International Agency for Research on Cancer
  • Kangdong Sacred Heart Hospital
  • Kosin University Gospel Hospital
  • Kyungpook National University Hospital
  • National Cancer Center, Korea
  • Pusan National University Hospital
  • SMG-SNU Boramae Medical Center
  • Uijeongbu St. Mary's Hospital/The Catholic University
Data source: National Cancer Center, Korea

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations