deltatrials
Completed PHASE3 INTERVENTIONAL 4-arm NCT02155660

Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History (TERRANOVA)

A Randomised, Double-blind, Double Dummy, 56 Week Placebo-controlled, Multicentre, Parallel Group, Phase 3 Study Evaluating Efficacy/Safety of 3 Benralizumab Doses in Patients With Moderate to Very Severe COPD With Previous Exacerbations.

Sponsor: AstraZeneca

Updated 14 times since 2017 Last updated: Jun 7, 2019 Started: Jun 25, 2014 Primary completion: Apr 9, 2018 Completion: Apr 9, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Moderate to Very Severe Chronic Obstructive Pulmonary Disease, this trial is completed. The trial is conducted by AstraZeneca and has accumulated 14 data snapshots since 2014. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~Jun 2017 · 3 months · monthly snapshot~Jun 2017 – ~Dec 2017 · 6 months · monthly snapshot~Dec 2017 – ~Mar 2018 · 3 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Jul 2019 · 13 months · monthly snapshot~Jul 2019 – ~Jan 2021 · 18 months · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – present · 8 months · monthly snapshot

Change History

14 versions recorded
  1. Nov 2025 — Present [monthly]

    Completed PHASE3

  2. Oct 2025 — Nov 2025 [monthly]

    Completed PHASE3

  3. Sep 2025 — Oct 2025 [monthly]

    Completed PHASE3

  4. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  5. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

Show 9 earlier versions
  1. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  2. Jul 2019 — Jan 2021 [monthly]

    Completed PHASE3

  3. Jun 2018 — Jul 2019 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  4. Mar 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

  5. Dec 2017 — Mar 2018 [monthly]

    Active Not Recruiting PHASE3

  6. Jun 2017 — Dec 2017 [monthly]

    Active Not Recruiting PHASE3

  7. Mar 2017 — Jun 2017 [monthly]

    Active Not Recruiting PHASE3

  8. Feb 2017 — Mar 2017 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  9. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Jun 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • MedImmune LLC
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .