A Study Of PF-05280014 Or Trastuzumab Plus Taxotere® And Carboplatin In HER2 Positive Breast Cancer In The Neoadjuvant Setting (REFLECTIONS B327-04)
A RANDOMIZED, DOUBLE-BLIND PHARMACOKINETIC STUDY OF PF-05280014 PLUS TAXOTERE (REGISTERED) AND CARBOPLATIN VERSUS HERCEPTIN (REGISTERED) PLUS TAXOTERE (REGISTERED) AND CARBOPLATIN FOR THE NEOADJUVANT TREATMENT OF PATIENTS WITH OPERABLE HER2-POSITIVE BREAST CANCER
Sponsor: Pfizer
This PHASE3 trial investigates Early Breast Cancer and is currently completed. Pfizer leads this study, which shows 10 recorded versions since 2014 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.
Status Flow
Change History
10 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE3
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Sep 2024 — Sep 2025 [monthly]
Completed PHASE3
-
Jul 2024 — Sep 2024 [monthly]
Completed PHASE3
-
Dec 2021 — Jul 2024 [monthly]
Completed PHASE3
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Jan 2021 — Dec 2021 [monthly]
Completed PHASE3
▶ Show 5 earlier versions
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Feb 2019 — Jan 2021 [monthly]
Completed PHASE3
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Jun 2018 — Feb 2019 [monthly]
Completed PHASE3
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May 2017 — Jun 2018 [monthly]
Completed PHASE3
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Feb 2017 — May 2017 [monthly]
Completed PHASE3
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Jan 2017 — Feb 2017 [monthly]
Completed PHASE3
First recorded
Sep 2014
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Pfizer
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Belgrade, Serbia , Bratislava, Slovakia , Budapest, Hungary , Chernihiv, Ukraine , Dnipropetrovsk, Ukraine , Fountain Valley, United States , Gdynia, Poland , Hradec Králové, Czechia , Irkutsk, Russia , Kecskemét, Hungary and 28 more locations