deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT02215512

Dose-Escalation Study of RRx-001 in Combination With Whole Brain Radiation in Subjects With Brain Metastases (BRAINSTORM)

A Phase 1 Dose-Escalation Study of RRx-001 in Combination With Whole Brain Radiation in Subjects With Brain Metastases (BRAINSTORM)

Sponsor: EpicentRx, Inc.

Interventions RRx-001 + WBRT
Updated 12 times since 2017 Last updated: Nov 1, 2021 Started: Feb 6, 2015 Primary completion: Nov 28, 2016 Completion: Nov 12, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Brain Metastases and is currently completed. EpicentRx, Inc. leads this study, which shows 12 recorded versions since 2015 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshotRecruiting~Aug 2017 – ~Jun 2018 · 10 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshotActive Not Recruiting~Jul 2018 – ~Dec 2019 · 17 months · monthly snapshotActive Not Recruiting~Dec 2019 – ~Aug 2020 · 8 months · monthly snapshotActive Not Recruiting~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotActive Not Recruiting~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Dec 2021 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  5. Jan 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE1

Show 7 earlier versions
  1. Aug 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  2. Dec 2019 — Aug 2020 [monthly]

    Active Not Recruiting PHASE1

  3. Jul 2018 — Dec 2019 [monthly]

    Active Not Recruiting PHASE1

  4. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE1

  5. Aug 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  6. Feb 2017 — Aug 2017 [monthly]

    Recruiting PHASE1

  7. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Feb 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • EpicentRx, Inc.
Data source: EpicentRx, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .