deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT02801097

RRx-001 in Combination With Irinotecan in Metastatic or Advanced Cancer (PAYLOAD) (PAYLOAD)

A Phase I, Open-Label, Multiple Ascending Dose Study to Assess the Safety and Tolerability of RRx-001 in Combination With Irinotecan in Metastatic or Advanced Cancer Patients Without Life-Prolonging Therapies of Demonstrated Clinical Benefit (PAYLOAD)

Sponsor: EpicentRx, Inc.

Updated 11 times since 2017 Last updated: May 12, 2022 Started: Aug 30, 2016 Primary completion: Nov 22, 2018 Completion: Dec 9, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Sufficient patients enrolled to end study

This PHASE1 trial investigates Advanced Cancer and Malignant Solid Tumor and is currently terminated or withdrawn. EpicentRx, Inc. leads this study, which shows 11 recorded versions since 2016 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotNot Yet Recruiting~Feb 2017 – ~Oct 2017 · 8 months · monthly snapshotNot Yet Recruiting~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshotRecruiting~Jun 2018 – ~Apr 2019 · 10 months · monthly snapshotRecruiting~Apr 2019 – ~Dec 2019 · 8 months · monthly snapshotActive Not Recruiting~Dec 2019 – ~Aug 2020 · 8 months · monthly snapshotActive Not Recruiting~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Jun 2022 · 17 months · monthly snapshotActive Not Recruiting~Jun 2022 – ~Jul 2024 · 25 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Jun 2022 — Jul 2024 [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  4. Jan 2021 — Jun 2022 [monthly]

    Active Not Recruiting PHASE1

  5. Aug 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

Show 6 earlier versions
  1. Dec 2019 — Aug 2020 [monthly]

    Active Not Recruiting PHASE1

  2. Apr 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  3. Jun 2018 — Apr 2019 [monthly]

    Recruiting PHASE1

  4. Oct 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  5. Feb 2017 — Oct 2017 [monthly]

    Not Yet Recruiting PHASE1

  6. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Aug 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • EpicentRx, Inc.
Data source: EpicentRx, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .