deltatrials
Completed PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT02231879

Plerixafor Versus G-CSF in the Treatment of People With WHIM Syndrome

A Phase III Double-Blind Randomized Crossover Study of Plerixafor Versus G-CSF in the Treatment of Patients With WHIM Syndrome.

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Conditions Hypogammaglobulinemia Infections Myelokathexis Neutropenia Warts
Interventions G-CSF Plerixafor
Updated 26 times since 2017 Last updated: Apr 6, 2023 Started: Oct 14, 2014 Primary completion: Oct 8, 2020 Completion: Feb 24, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02231879, this PHASE2/PHASE3 trial focuses on Hypogammaglobulinemia and Infections and remains completed. Sponsored by National Institute of Allergy and Infectious Diseases (NIAID), it has been updated 26 times since 2014, reflecting substantial change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Dec 2019 · 6 months · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~May 2020 · 2 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Nov 2020 · 3 months · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2023 · 25 months · monthly snapshot~May 2023 – ~Jul 2024 · 14 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

26 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2/PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2/PHASE3

    Phase: PHASE2_PHASE3 → PHASE2/PHASE3

  3. May 2023 — Jul 2024 [monthly]

    Completed PHASE2_PHASE3

  4. Apr 2021 — May 2023 [monthly]

    Completed PHASE2_PHASE3

  5. Mar 2021 — Apr 2021 [monthly]

    Completed PHASE2_PHASE3

    Status: Active Not Recruiting → Completed

▶ Show 21 earlier versions

  1. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  2. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  3. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  4. Aug 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  5. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  6. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  7. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  8. Mar 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  9. Jan 2020 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  10. Dec 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  11. Jun 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    Phase: PHASE3 → PHASE2_PHASE3

  12. May 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE3

  13. Apr 2019 — May 2019 [monthly]

    Active Not Recruiting PHASE3

  14. Feb 2019 — Apr 2019 [monthly]

    Active Not Recruiting PHASE3

  15. Nov 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE3

  16. Sep 2018 — Nov 2018 [monthly]

    Active Not Recruiting PHASE3

  17. Aug 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  18. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

  19. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE3

  20. Feb 2017 — Jun 2018 [monthly]

    Recruiting PHASE3

  21. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Oct 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Allergy and Infectious Diseases (NIAID)
Data source: National Institutes of Health Clinical Center (CC)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations