deltatrials
Terminated PHASE3 INTERVENTIONAL 1-arm NCT02245568

Open-Label Study of Leuco-methylthioninium Bis(Hydromethanesulfonate) (LMTM) in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)

An Open-Label, Extension Study of the Effects of LMTM in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)

Sponsor: TauRx Therapeutics Ltd

Interventions LMTM
Updated 11 times since 2017 Last updated: May 22, 2023 Started: Aug 31, 2014 Primary completion: May 31, 2017 Completion: May 31, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This study has been terminated for administrative reasons only.

Listed as NCT02245568, this PHASE3 trial focuses on Alzheimer's Disease and Behavioral Variant Frontotemporal Dementia and remains terminated or withdrawn. Sponsored by TauRx Therapeutics Ltd, it has been updated 11 times since 2014, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotEnrolling By Invitation~Feb 2017 – ~Mar 2018 · 13 months · monthly snapshotEnrolling By Invitation~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshotTerminated~Jun 2018 – ~Jul 2020 · 25 months · monthly snapshotTerminated~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshotTerminated~Jan 2021 – ~Jun 2023 · 29 months · monthly snapshotTerminated~Jun 2023 – ~Jul 2024 · 13 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 7 months · monthly snapshotTerminated~Jan 2026 – present · 3 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Jan 2026 — Present [monthly]

    Terminated PHASE3

  2. Sep 2025 — Present [monthly]

    Terminated PHASE3

  3. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  5. Jun 2023 — Jul 2024 [monthly]

    Terminated PHASE3

Show 6 earlier versions
  1. Jan 2021 — Jun 2023 [monthly]

    Terminated PHASE3

  2. Jul 2020 — Jan 2021 [monthly]

    Terminated PHASE3

  3. Jun 2018 — Jul 2020 [monthly]

    Terminated PHASE3

  4. Mar 2018 — Jun 2018 [monthly]

    Terminated PHASE3

    Status: Enrolling By InvitationTerminated

  5. Feb 2017 — Mar 2018 [monthly]

    Enrolling By Invitation PHASE3

  6. Jan 2017 — Feb 2017 [monthly]

    Enrolling By Invitation PHASE3

    First recorded

Aug 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • TauRx Therapeutics Ltd
Data source: TauRx Therapeutics Ltd

For direct contact, visit the study record on ClinicalTrials.gov .