deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT02255799

Multicenter Evaluation of Memory Remediation After TBI With Donepezil (MEMRI-TBI-D)

Four-site, Randomized, Parallel Design, Double-blind, Placebo-controlled, 10-week Trial of Donepezil 10 mg Daily for Verbal Memory Problems Among Adults With TBI in the Subacute or Chronic Recovery Period

Sponsor: Albert Einstein Healthcare Network

Conditions Memory Deficits Traumatic Brain Injury
Interventions Donepezil Placebo
Updated 17 times since 2017 Last updated: Jan 13, 2025 Started: Sep 1, 2013 Primary completion: Dec 4, 2024 Completion: Dec 4, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Memory Deficits and Traumatic Brain Injury and is currently completed. Albert Einstein Healthcare Network leads this study, which shows 17 recorded versions since 2013 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Jan 2019 · 7 months · monthly snapshot~Jan 2019 – ~Jan 2020 · 12 months · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Dec 2020 · 10 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Apr 2022 · 11 months · monthly snapshot~Apr 2022 – ~Sep 2022 · 5 months · monthly snapshot~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshot~Mar 2023 – ~Oct 2023 · 7 months · monthly snapshot~Oct 2023 – ~Feb 2024 · 4 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – present · 17 months · monthly snapshot

Change History

17 versions recorded

  1. Feb 2025 — Present [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

  2. Sep 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  4. Feb 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Oct 2023 — Feb 2024 [monthly]

    Active Not Recruiting PHASE3

▶ Show 12 earlier versions

  1. Mar 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE3

  2. Sep 2022 — Mar 2023 [monthly]

    Active Not Recruiting PHASE3

  3. Apr 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE3

  4. May 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE3

  5. Jan 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE3

  6. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  7. Feb 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE3

  8. Jan 2020 — Feb 2020 [monthly]

    Active Not Recruiting PHASE3

  9. Jan 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  10. Jun 2018 — Jan 2019 [monthly]

    Recruiting PHASE3

  11. Feb 2017 — Jun 2018 [monthly]

    Recruiting PHASE3

  12. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Sep 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Albert Einstein Healthcare Network
  • Baylor College of Medicine
  • Craig Hospital
  • Indiana University
  • Spaulding Rehabilitation Hospital
  • TIRR Memorial Hermann
Data source: Baylor College of Medicine

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations