deltatrials
Completed PHASE1/PHASE2 NCT02312011

A Safety andTolerability Study of Multiple Doses of ISIS-DMPKRx in Adults With Myotonic Dystrophy Type 1

A Phase 1/2a Blinded, Placebo-Controlled Study to Assess the Safety, Tolerability, and Dose-range Finding of Multiple Ascending Doses of ISIS 598769 Administered Subcutaneously to Adult Patients With Myotonic Dystrophy Type 1

Sponsor: Ionis Pharmaceuticals, Inc.

Updated 9 times since 2017 Last updated: Dec 1, 2022 Started: Dec 31, 2014 Primary completion: Jul 31, 2016 Completion: Aug 31, 2016

A PHASE1/PHASE2 clinical study on Myotonic Dystrophy Type 1, this trial is completed. The trial is conducted by Ionis Pharmaceuticals, Inc. and has accumulated 9 data snapshots since 2014. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Change History

9 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Apr 2022 — Jan 2023 [monthly]

    Completed PHASE1_PHASE2

  5. Jan 2021 — Apr 2022 [monthly]

    Completed PHASE1_PHASE2

Show 4 earlier versions
  1. Jul 2018 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

  2. Jun 2018 — Jul 2018 [monthly]

    Completed PHASE1_PHASE2

  3. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE1_PHASE2

  4. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE1_PHASE2

    First recorded

Dec 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Ionis Pharmaceuticals, Inc.
Data source: Ionis Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

  • Baltimore, United States
  • Columbus, United States
  • Gainesville, United States
  • Houston, United States
  • Kansas City, United States
  • Rochester, United States
  • Salt Lake City, United States
  • Stanford, United States