deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 1-arm NCT02339922

Ixazomib Citrate and Rituximab in Treating Patients With Indolent B-cell Non-Hodgkin Lymphoma

A Window Study of Ixazomib in Untreated Indolent B-NHL

Sponsor: Millennium Pharmaceuticals, Inc.

Conditions Chronic Lymphocytic Leukemia Follicular Lymphoma Lymphoplasmacytic Lymphoma Mantle Cell Lymphoma Marginal Zone Lymphoma Recurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue Refractory Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue Small Lymphocytic Lymphoma Waldenstrom Macroglobulinemia
Interventions Ixazomib Citrate Laboratory Biomarker Analysis Rituximab
Updated 26 times since 2017 Last updated: Feb 12, 2026 Started: May 19, 2016 Primary completion: Dec 30, 2024 Completion: Jan 6, 2031
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Chronic Lymphocytic Leukemia and Follicular Lymphoma and is currently ongoing. Millennium Pharmaceuticals, Inc. leads this study, which shows 26 recorded versions since 2016 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Feb 2018 · 12 months · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Mar 2019 · 8 months · monthly snapshot~Mar 2019 – ~Jun 2019 · 3 months · monthly snapshot~Jun 2019 – ~Nov 2019 · 5 months · monthly snapshot~Nov 2019 – ~Feb 2020 · 3 months · monthly snapshot~Feb 2020 – ~Apr 2020 · 2 months · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Aug 2020 · 2 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Nov 2021 · 6 months · monthly snapshot~Nov 2021 – ~May 2022 · 6 months · monthly snapshot~May 2022 – ~Nov 2022 · 6 months · monthly snapshot~Nov 2022 – ~Jun 2023 · 7 months · monthly snapshot~Jun 2023 – ~Dec 2023 · 6 months · monthly snapshot~Dec 2023 – ~Jun 2024 · 6 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Feb 2025 · 2 months · monthly snapshot~Feb 2025 – ~Mar 2026 · 13 months · monthly snapshot~Mar 2026 – present · 6 months · monthly snapshot

Change History

26 versions recorded

  1. Mar 2026 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Feb 2025 — Mar 2026 [monthly]

    Active Not Recruiting PHASE2

  3. Dec 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

▶ Show 21 earlier versions

  1. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Dec 2023 — Jun 2024 [monthly]

    Active Not Recruiting PHASE2

  3. Jun 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE2

  4. Nov 2022 — Jun 2023 [monthly]

    Active Not Recruiting PHASE2

  5. May 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE2

  6. Nov 2021 — May 2022 [monthly]

    Active Not Recruiting PHASE2

  7. May 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE2

  8. Jan 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE2

  9. Aug 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  10. Jun 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  11. Apr 2020 — Jun 2020 [monthly]

    Recruiting PHASE2

  12. Feb 2020 — Apr 2020 [monthly]

    Recruiting PHASE2

  13. Nov 2019 — Feb 2020 [monthly]

    Recruiting PHASE2

  14. Jun 2019 — Nov 2019 [monthly]

    Recruiting PHASE2

  15. Mar 2019 — Jun 2019 [monthly]

    Recruiting PHASE2

  16. Jul 2018 — Mar 2019 [monthly]

    Recruiting PHASE2

  17. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  18. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  19. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE2

  20. Feb 2017 — Feb 2018 [monthly]

    Recruiting PHASE2

  21. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

May 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Millennium Pharmaceuticals, Inc.
  • University of Washington
Data source: University of Washington

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations