deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT02374645

A Phase I Study of Safety and Pharmacokinetics of Volitinib in Combination With Gefitinib in EGFR(+) NSCLC

A Phase Ib, Open-label, Multi-centre Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumour Activity of Volitinib in Combination With Gefitinib in Patients With Epidermal Growth Factor Receptor-mutated Non-small Cell Lung Cancer Who Have Progressed on Epidermal Growth Factor Receptor Inhibitor Treatment

Sponsor: AstraZeneca

Updated 9 times since 2017 Last updated: Apr 20, 2020 Started: Apr 30, 2015 Primary completion: Feb 18, 2018 Completion: Sep 14, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Non-Small Cell Lung Cancer, this trial is completed. The trial is conducted by AstraZeneca and has accumulated 9 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Jul 2017 · 6 months · monthly snapshotRecruiting~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshotActive Not Recruiting~Feb 2019 – ~May 2020 · 15 months · monthly snapshotActive Not Recruiting~May 2020 – ~Jan 2021 · 8 months · monthly snapshotCompleted~Jan 2021 – ~Nov 2022 · 22 months · monthly snapshotCompleted~Nov 2022 – ~Jul 2024 · 20 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Nov 2022 — Jul 2024 [monthly]

    Completed PHASE1

  4. Jan 2021 — Nov 2022 [monthly]

    Completed PHASE1

  5. May 2020 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 4 earlier versions
  1. Feb 2019 — May 2020 [monthly]

    Active Not Recruiting PHASE1

  2. Jun 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE1

  3. Jul 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. Jan 2017 — Jul 2017 [monthly]

    Recruiting PHASE1

    First recorded

Apr 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • Hutchison Medipharma Limited
Data source: Hutchmed

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations