deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT02386397

Activity of Regorafenib in Combination With Chemotherapy in Patients With Advanced Biliary Tract Cancer (BREGO)

Activity of Regorafenib in Combination With Modified Gemcitabine - Oxaliplatin Chemotherapy (mGEMOX) in Patients With Advanced Biliary Tract Cancer (BTC): A Phase Ib-II Trial (BREGO)

Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle

Conditions Digestive Cancer
Interventions GEMOX Regorafenib
Updated 8 times since 2017 Last updated: Mar 10, 2026 Started: Sep 30, 2014 Primary completion: Dec 31, 2019 Completion: Dec 31, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02386397, this PHASE1/PHASE2 trial focuses on Digestive Cancer and remains completed. Sponsored by Institut du Cancer de Montpellier - Val d'Aurelle, it has been updated 8 times since 2014, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotRecruiting~Jun 2018 – ~Sep 2019 · 15 months · monthly snapshotRecruiting~Sep 2019 – ~Feb 2020 · 5 months · monthly snapshotUnknown Status~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Mar 2026 · 18 months · monthly snapshotCompleted~Mar 2026 – present · 6 months · monthly snapshotCompleted

Change History

8 versions recorded

  1. Mar 2026 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Sep 2024 — Mar 2026 [monthly]

    Completed PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  5. Feb 2020 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

    Status: Unknown Status → Completed

▶ Show 3 earlier versions

  1. Sep 2019 — Feb 2020 [monthly]

    Unknown Status PHASE1_PHASE2

    Status: Recruiting → Unknown Status

  2. Jun 2018 — Sep 2019 [monthly]

    Recruiting PHASE1_PHASE2

  3. Jan 2017 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Sep 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Institut du Cancer de Montpellier - Val d'Aurelle
Data source: Institut du Cancer de Montpellier - Val d'Aurelle

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations