deltatrials
Completed PHASE1 INTERVENTIONAL 4-arm NCT02388620

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

A Phase I, Open Label, Multi-center, Parallel Cohort, Single Dose Study to Evaluate the Pharmacokinetics of LEE011 in Healthy Subjects With Normal Hepatic Function and Subjects With Impaired Hepatic Function.

Sponsor: Novartis Pharmaceuticals

Interventions LEE011
Updated 9 times since 2017 Last updated: Dec 16, 2020 Started: Mar 25, 2015 Primary completion: Jan 9, 2017 Completion: Jan 9, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02388620, this PHASE1 trial focuses on Impaired Hepatic Function and Normal Hepatic Function and remains completed. Sponsored by Novartis Pharmaceuticals, it has been updated 9 times since 2015, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshotCompleted~Jul 2017 – ~Jan 2018 · 6 months · monthly snapshotCompleted~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2019 · 7 months · monthly snapshotCompleted~Jan 2019 – ~Jan 2021 · 24 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Jan 2019 — Jan 2021 [monthly]

    Completed PHASE1

  5. Jun 2018 — Jan 2019 [monthly]

    Completed PHASE1

Show 4 earlier versions
  1. Jan 2018 — Jun 2018 [monthly]

    Completed PHASE1

  2. Jul 2017 — Jan 2018 [monthly]

    Completed PHASE1

  3. Feb 2017 — Jul 2017 [monthly]

    Completed PHASE1

    Status: RecruitingCompleted

  4. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Mar 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .