deltatrials
Completed PHASE1 INTERVENTIONAL 3-arm NCT04823702

Study of Aldafermin (NGM282) in Participants With Impaired Hepatic Function

A Phase I, Open-label, Parallel-group Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Single Dose of Aldafermin in Subjects With Impaired Hepatic Function

Sponsor: NGM Biopharmaceuticals, Inc

Interventions Aldafermin
Updated 5 times since 2021 Last updated: Jan 15, 2022 Started: Apr 1, 2021 Primary completion: Nov 19, 2021 Completion: Nov 19, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04823702, this PHASE1 trial focuses on Impaired Hepatic Function and remains completed. Sponsored by NGM Biopharmaceuticals, Inc, it has been updated 5 times since 2021, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~May 2021 – ~Feb 2022 · 9 months · monthly snapshotRecruiting~Feb 2022 – ~Jul 2024 · 29 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 19 months · monthly snapshotCompleted~Jan 2026 – present · 3 months · monthly snapshot

Change History

5 versions recorded
  1. Jan 2026 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Present [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Feb 2022 — Jul 2024 [monthly]

    Completed PHASE1

    Status: RecruitingCompleted

  5. May 2021 — Feb 2022 [monthly]

    Recruiting PHASE1

    First recorded

Apr 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • NGM Biopharmaceuticals, Inc
Data source: NGM Biopharmaceuticals, Inc

For direct contact, visit the study record on ClinicalTrials.gov .