deltatrials
Active Not Recruiting NA INTERVENTIONAL 2-arm NCT02401685

POSNOC - A Trial Looking at Axillary Treatment in Early Breast Cancer (POSNOC)

POSNOC - POsitive Sentinel NOde: Adjuvant Therapy Alone Versus Adjuvant Therapy Plus Clearance or Axillary Radiotherapy. A Randomised Controlled Trial of Axillary Treatment in Women With Early Stage Breast Cancer Who Have Metastases in One or Two Sentinel Nodes

Sponsor: Breast Cancer Trials, Australia and New Zealand

Conditions Breast Cancer
Interventions Adjuvant therapy Axillary treatment
Updated 15 times since 2017 Last updated: Jul 5, 2025 Started: Aug 1, 2014 Primary completion: Jul 31, 2026 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02401685, this NA trial focuses on Breast Cancer and remains ongoing. Sponsored by Breast Cancer Trials, Australia and New Zealand, it has been updated 15 times since 2014, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2018 · 13 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Mar 2019 · 9 months · monthly snapshot~Mar 2019 – ~Feb 2020 · 11 months · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Jan 2021 · 8 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Mar 2023 · 17 months · monthly snapshot~Mar 2023 – ~Mar 2024 · 12 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

15 versions recorded

  1. Sep 2025 — Present [monthly]

    Active Not Recruiting NA

  2. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting NA

  3. Sep 2024 — Aug 2025 [monthly]

    Active Not Recruiting NA

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting NA

  5. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting NA

▶ Show 10 earlier versions

  1. Mar 2023 — Mar 2024 [monthly]

    Active Not Recruiting NA

  2. Oct 2021 — Mar 2023 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  3. Sep 2021 — Oct 2021 [monthly]

    Recruiting NA

  4. Jan 2021 — Sep 2021 [monthly]

    Recruiting NA

  5. May 2020 — Jan 2021 [monthly]

    Recruiting NA

  6. Feb 2020 — May 2020 [monthly]

    Recruiting NA

  7. Mar 2019 — Feb 2020 [monthly]

    Recruiting NA

  8. Jun 2018 — Mar 2019 [monthly]

    Recruiting NA

  9. Feb 2018 — Jun 2018 [monthly]

    Recruiting NA

  10. Jan 2017 — Feb 2018 [monthly]

    Recruiting NA

    First recorded

Aug 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Breast Cancer Trials, Australia and New Zealand
  • NCRI Radiotherapy Trials QA Group (RTTQA)
  • Sussex Health Outcomes Research & Education in Cancer (SHORE-C)
  • University Hospitals of Derby and Burton NHS Foundation Trust
  • University of Nottingham
Data source: University Hospitals of Derby and Burton NHS Foundation Trust

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adelaide, Australia , Ashford, United Kingdom , Bankstown, Australia , Barnsley, United Kingdom , Belfast, United Kingdom , Birmingham, United Kingdom , Bolton, United Kingdom , Bradford, United Kingdom , Bridgend, United Kingdom , Brisbane, Australia and 36 more locations