deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT02410863

Biopsy- and Biology-driven Optimization of Targeted Therapy in Subjects With Advanced Melanoma (BOTTOM)

Biopsy- and Biology-driven Optimization of Targeted Therapy of Metastatic Melanoma in BRAF Inhibitor Non-pretreated and Pretreated Subjects With Advanced, Non-resectable (STAGE IIIC) or Metastatic (StAGE IV) BRAF Mutation-positive Melanoma

Sponsor: Prof. Dr. med. Dirk Schadendorf

Updated 8 times since 2017 Last updated: Oct 13, 2020 Started: Nov 30, 2015 Primary completion: Aug 31, 2018 Completion: Aug 31, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

lack of recruitment due to changed therapy options

This PHASE2 trial investigates Malignant Melanoma and is currently terminated or withdrawn. Prof. Dr. med. Dirk Schadendorf leads this study, which shows 8 recorded versions since 2015 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Dec 2017 · 11 months · monthly snapshotRecruiting~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotRecruiting~Jun 2018 – ~Jan 2019 · 7 months · monthly snapshotRecruiting~Jan 2019 – ~Nov 2020 · 22 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 24 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  4. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE2

  5. Jan 2019 — Nov 2020 [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

Show 3 earlier versions
  1. Jun 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  2. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  3. Jan 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

    First recorded

Nov 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Prof. Dr. med. Dirk Schadendorf
Data source: University Hospital, Essen

For direct contact, visit the study record on ClinicalTrials.gov .